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English
Springer-Verlag New York Inc.
24 October 2012
Heart transplantation remains one of the major scientific

achievements of twentieth century medicine. During the past four

decades, it has evolved from an unproven experimental surgical

technique to the most effective form of therapy for refractory

end-stage heart disease. It has captured the public's imagination and

expanded our understanding of fundamental immunologic mechanisms that

are responsible for cellular and humorally-mediated immunity. Despite

its successes, many clinical and scientific problems remain. One or

more bouts of acute cellular or humoral (vascular) rejection will

occur in over 75% of transplant recipients despite current

immunosuppressive strategies. Further, rejection directly results in

approximately 20% of post-transplant deaths and is believed to play a

major role in the development of late allograft dysfunction and

coronary vasculopathy.

This book by international experts in the fields of transplantation

medicine, immunobiology and cardiac imaging provides the reader with

an up-to-date, consise summary of the latest developments in the

diagnosis and treatment of acute cardiac rejection. It is axiomatic

that a more complete understanding of the pathogenic processes

involved in rejection will ultimately lead to its prevention. This

volume will be useful to transplant cardiologists, cardiovascular

surgeons, cardiac pathologists and transplant scientists who seek to

prolong the lifespan and improve the quality of life of their

transplant recipients.
Edited by:   , , ,
Imprint:   Springer-Verlag New York Inc.
Country of Publication:   United States
Edition:   Softcover reprint of the original 1st ed. 2001
Dimensions:   Height: 235mm,  Width: 155mm,  Spine: 23mm
Weight:   694g
ISBN:   9781461356592
ISBN 10:   1461356598
Pages:   434
Publication Date:  
Audience:   Professional and scholarly ,  Undergraduate
Format:   Paperback
Publisher's Status:   Active

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