Heart transplantation remains one of the major scientific
achievements of twentieth century medicine. During the past four
decades, it has evolved from an unproven experimental surgical
technique to the most effective form of therapy for refractory
end-stage heart disease. It has captured the public's imagination and
expanded our understanding of fundamental immunologic mechanisms that
are responsible for cellular and humorally-mediated immunity. Despite
its successes, many clinical and scientific problems remain. One or
more bouts of acute cellular or humoral (vascular) rejection will
occur in over 75% of transplant recipients despite current
immunosuppressive strategies. Further, rejection directly results in
approximately 20% of post-transplant deaths and is believed to play a
major role in the development of late allograft dysfunction and
coronary vasculopathy.
This book by international experts in the fields of transplantation
medicine, immunobiology and cardiac imaging provides the reader with
an up-to-date, consise summary of the latest developments in the
diagnosis and treatment of acute cardiac rejection. It is axiomatic
that a more complete understanding of the pathogenic processes
involved in rejection will ultimately lead to its prevention. This
volume will be useful to transplant cardiologists, cardiovascular
surgeons, cardiac pathologists and transplant scientists who seek to
prolong the lifespan and improve the quality of life of their
transplant recipients.
Edited by:
G. William Dec, Jagat Narula, Manel Ballester, Ignasi Carrio Imprint: Springer-Verlag New York Inc. Country of Publication: United States Edition: Softcover reprint of the original 1st ed. 2001 Dimensions:
Height: 235mm,
Width: 155mm,
Spine: 23mm
Weight: 694g ISBN:9781461356592 ISBN 10: 1461356598 Pages: 434 Publication Date:24 October 2012 Audience:
Professional and scholarly
,
Undergraduate
Format:Paperback Publisher's Status: Active