Cancer on Trial

Oncology as a New Style of Practice

Peter Keating, Alberto Cambrosio

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English

University of Chicago Press
18 April 2014

Clinical trials; Oncology

Until the early 1960s, cancer treatment consisted primarily of surgery and radiation therapy. Most practitioners then viewed the treatment of terminally ill cancer patients with heroic courses of chemotherapy as highly questionable. The randomized clinical trials that today sustain modern oncology were relatively rare and prompted stiff opposition from physicians, who were loath to assign patients randomly to competing treatments. Yet today these trials form the basis of medical oncology. How did such a spectacular change occur? How did medical oncology pivot from a nonentity and, in some regards, a reviled practice to the central position it now occupies in modern medicine?

In Cancer on Trial Peter Keating and Alberto Cambrosio explore how practitioners established a new style of practice, at the center of which lies the cancer clinical trial. Far from mere testing devices, these trials have become full-fledged experiments that have redefined the practices of clinicians, statisticians, and biologists. Keating and Cambrosio investigate these trials and how they have changed since the 1960s, all the while demonstrating their significant impact on the progression of oncology. A novel look at the institution of clinical cancer research and therapy, this book will be warmly welcomed by historians, sociologists, and anthropologists of science and medicine, as well as clinicians and researchers in the cancer field.

By: Peter Keating, Alberto Cambrosio
Imprint: University of Chicago Press
Country of Publication: United States
Dimensions: Height: 23mm, Width: 15mm, Spine: 3mm
Weight: 709g
ISBN: 9780226143040
ISBN 10: 022614304X
Pages: 480
Publication Date: 18 April 2014
Audience: College/higher education , Professional and scholarly , Further / Higher Education , Undergraduate
Format: Paperback
Publisher's Status: Active

Peter Keating is professor of history at the Universite du Quebec a Montreal. Alberto Cambrosio is professor in the Department of Social Studies of Medicine at McGill University. Together, they are the authors of Exquisite Specificity and Biomedical Platforms.

Reviews for Cancer on Trial: Oncology as a New Style of Practice

Keating and Cambrosio have made a major contribution to this area and scholars of any stripe working on cancer or biomedicine, and even the further-flung fields of statistics and molecular biology, will benefit from reckoning with its insights. --Robin Wolfe Scheffl er, Yale University Medical History