Craig Mallinckrodt is a Distinguished Biostatistician at Pentara Corporation.. He is a Fellow of the American Statistical Association and he won the Royal Statistical Society’s award for outstanding contribution to the pharmaceutical industry. He has extensive industry and academic working experience, holding technical positions from entry level to Vice President. Craig has led industry working groups and he has published extensively on a wide variety of clinical and methodological topics, most notably, missing data, estimands, and various aspects of clinical development optimization.