Bladder cancer represents a significant cause of morbidity and mortality worldwide and presents major problems in detection and management. This book will review comprehensively the current understanding of the biology, pathophysiology and urological oncology of the disease, looking at the problems and potential solutions. Fully illustrated including a colour plate section, it will include chapters on both the scientific and clinical principles, emphasising molecular biology, pathogenesis, detection and experimental therapeutics, and focusing on new developments in clinical research. The contributors are international and well known in the area.
Introduction ; Surgical anatomy of the bladder ; Epidemiology of bladder cancer ; Screening for bladder cancer ; Animal models for the study of bladder cancer ; Pathology of bladder cancer ; Biology of bladder cancer ; The role of adhesion molecules in bladder cancer pathology ; Clinical presentation and investigation of bladder cancer ; Prognostic factors in the management of invasive bladder cancer ; The management of superficial bladder cancer ; Surgical treatment of muscle-invasive bladder cancer ; Radiotherapy in the management of muscle-invasive bladder cancer ; Systemic chemotherapy of muscle-invasive bladder cancer ; Integration of cytotoxic chemotherapy into management of muscle-invasive bladder cancer ; Intravesical chemotherapy of bladder cancer ; Immunotherapy of bladder cancer ; Novel therapeutic strategies for bladder cancer ; Gene therapy of bladder cancer ; Locally induced hyperthermia in bladder cancer ; Alternative urinary resevoirs and conduits: state of the science ; Palliative care for patients with bladder cancer ; The role of the research nurse in the management of bladder cancer patients