This text is intended to serve as a practical guide to muscle pathology, particularly for histopathologists and for those in training. In this edition, the authors have taken account of advances in classification and in histological techniques, as well as new knowledge of neuromuscular diseases that have emerged since the first edition was published in 1984. The book should continue to be of value as a practical guide in the diagnosis and understanding of these disorders, and should be available in every hospital histopathology laboratory in which muscle biopsies are examined. This book should be of interest to muscle pathologists, general histopathologists and trainees.
By:
Michael Swash,
Martin S. Schwartz
Imprint: Hodder Arnold
Country of Publication: United Kingdom
Edition: 2nd New edition
Dimensions:
Height: 235mm,
Width: 155mm,
Spine: 13mm
Weight: 385g
ISBN: 9780412348808
ISBN 10: 0412348802
Series: Biopsy Pathology Series
Pages: 237
Publication Date: 01 January 1991
Audience:
College/higher education
,
Professional and scholarly
,
Further / Higher Education
,
Undergraduate
Format: Paperback
Publisher's Status: Active
Introduction - general features of muscle, the motor unit, classifications of neuromuscular disorders, indications for muscle biopsy, selection for muscle biopsy, clinical features of neuromuscular disease, clinical investigation of neuromuscular disorders; the muscle biopsy - techniques and laboratory methods - preperation of the biopsy, cutting sections, histological methods, histological techniques for other structures found in muscle; histological and morphometric characteristics of normal muscle - fibre size, fibre-type distribution, fibre-type predominance, histological features; histological features of myopathic and neurogenic disorders - myopathic disorders, neurogenic disorders; inflammatory myopathies - clinical features of inflammatory myopathies, laboratory investigations, pathology, muscle involvement in other autoimmune disorders; muscular dystrophies - Duchenne muscular dysrophy, Becker muscular dystrophy, other X-linked dystrophies, limb-girdle muscular dystrophy, fascioscapulohumeral muscular dystrophy, Distal myopthies, myotonic dystrophy, Ocular myopathies and ocularpharyngeal dystrophy; 'benign' myopathies of childhood - Nemaline myopathy, central core disease, centronuclear (myotubular) myopathy, congenital fibre-type disproportion, myopathy with tubular aggregates, failure of fibre-types differentation, other benign myopathies of childhood, congenital muscular dystrophy; metabolic, endocrine and drug-induced myopathies - Metabolic myopathies, endocrine myopathies, drug-induced myopthies; neurogenic disorders - spinal muscular atropathies, motor neuron disease, other disorders of anterior horn cells and ventral roots, polyneuropathies, mononeuropathies; tumours of striated muscle and related disorders - primary tumours arising in muscle, tumours of muscle, fibrous tissue, fibrohistiocytic tumours, tumours of fat, blood vessels, peripheral nerves, other tumours that may arise in muscle, masses that mimic tumours (pseudotumours); interpretation of the muscle biopsy - is the biopsy abnormal?, myopathic or neurogenic?, specific morphological changes in myopthies, significance of some morphological abnormalities in muscle fibres, relation of pathological change to clinical disability or stage of disorder, are sequential biopsies useful?.
