Biosynthesis, chemical synthesis, combinatorial synthesis, enzymatic synthesis, enzymes and genetics are subjects of considerable interest. These themes are dealt with in three areas of current bioorganic research. Deoxysugars and deoxy- oligosaccharides are important structural moieties in bio- active natural products. What is their contribution to the mode of action and how can they be studied? Synthetic strategies, biosynthesis and the genetics involved are presented. The second review article, on non-template based multienzyme systems, addresses the question why polyketides are the most diverse group of natural products. Polyketide syntheses are compared with other non-template multienzyme systems. The third review article deals with angucycline antibiotics, the largest subgroup of polycyclic aromatic polyketides.
Edited by:
J. Rohr
Imprint: Springer-Verlag Berlin and Heidelberg GmbH & Co. K
Country of Publication: Germany
Edition: 1st ed. 1997. 2nd printing 2000
Dimensions:
Height: 235mm,
Width: 155mm,
Spine: 11mm
Weight: 670g
ISBN: 9783540669715
ISBN 10: 354066971X
Series: Springer Desktop Editions in Chemistry
Pages: 195
Publication Date: 14 February 2000
Audience:
College/higher education
,
Professional and scholarly
,
Professional & Vocational
,
A / AS level
,
Further / Higher Education
Format: Paperback
Publisher's Status: Active
Chemical and biochemical aspects of deoxysugars and deoxysugar oligosaccharides.- The chemistry and biology of fatty acid, polyketide, and nonribosomal peptide biosynthesis.- Angucyclines: Total syntheses, new structures, and biosynthetic studies of an emerging new class of antibiotics.
