Biomolecular Action of Ionizing Radiation

Shirley Lehnert

$378

Hardback

Not in-store but you can order this
How long will it take?

Availability Information

We source books from suppliers in Australia and overseas. For books we don't currently have in stock, the time it takes to get them from our suppliers can vary widely - from a few days to a few months - so we check each book with each supplier to determine the expected time it will take to be supplied to us.

We then advise you accordingly. If the time taken to get any book is too long for you, you can let us know and we will cancel or adjust your order, and refund as required.

To find out the anticipated arrival time for specific items prior to ordering, please contact us by phone or email:

Phone +61 2 9264 3111, or 1800 4 BOOKS (1800 4 26657) if outside Sydney:
option 1 Abbey's Bookshop (Crime, History, Science, Kids & more) • info@abbeys.com.au
option 2 Language Book Centre (ESL & Foreign Languages) • language@abbeys.com.au
option 3 Galaxy Bookshop (Sci-fi, Fantasy, Romance, Graphic Novels) • sf@galaxybooks.com.au

QTY:

English

CRC Press
04 April 2018

Therapy & therapeutics

Series: Series in Medical Physics and Biomedical Engineering

Embracing the transformation of radiation sciences by the recent surge of developments in molecular biology, this progressive text offers an up-to-date analysis of in vitro and in vivo molecular responses in the body induced by ionizing radiation. With a unique emphasis on medical physics applications, Biomolecular Action of Ionizing Radiation also presents a much needed, in-depth perspective on clinical applications for the treatment of cancer and radiation injuries.

Based on a popular course given by the author at McGill University,the bookplaces the traditional tenets of radiation biology in the context of contemporary cell and molecular biology. Using terms that non-experts in molecular biology can understand, it clarifies the underlying mechanisms of radiation effects on molecular interactions including signal transduction pathways, modes of cell killing, and non-targeted effects. The author subsequently associates key principles and advances with potential applications, including the use of ionizing radiation as a cytotoxic and cytostatic agent, and radiosensitization by targeting molecular intermediates or signaling molecules involved in radiation-induced processes.

Raising the standard for radiation biology texts that are currently available, Biomolecular Action of Ionizing Radiation is an outstanding resource for advanced undergraduate and graduate students in medical physics, radiation oncology, radiation biology, and those who have an interest in the radiation sciences and in cancer treatment.

By: Shirley Lehnert
Imprint: CRC Press
Country of Publication: United Kingdom
Dimensions: Height: 234mm, Width: 156mm,
Weight: 453g
ISBN: 9781138407398
ISBN 10: 1138407399
Series: Series in Medical Physics and Biomedical Engineering
Pages: 562
Publication Date: 04 April 2018
Audience: College/higher education , Primary
Format: Hardback
Publisher's Status: Active

Introduction. Basic radiation physics and chemistry. Basic cell biology and molecular genetics. Methods of cell and molecular radiobiology. Ionizing radiation effects to the cytoplasm. Damage to DNA by ionizing radiation. Repair of radiation damage to DNA. Cellular response to DNA damage. Chromatin structure and radiation sensitivity. Radiation-induced chromosome damage. Modulation of radiation response via signal transduction pathways. Radiation-induced apoptosis. Early and late responding genes induced by ionizing radiation. Cell death, cell survival, and adaptation. Bystander effects and genomic instability. Tumor radiobiology. Radiation biology of nonmammalian species: three eukaryotes and a bacterium.References. Glossary. Index.

Shirley Lehnert

Reviews for Biomolecular Action of Ionizing Radiation

... The new textbook is targeted at students in radiation oncology and medical physics and should be a useful resource for graduate students with interests in radiation sciences and cancer treatment. ... Overall, I felt the author has generally achieved the aim of developing a textbook on applications of molecular biology to radiation biology relating to radiation oncology. ... -Crystallography Reviews, Vol. 15, No. 2, April-June 2009 The major strength of this book likes in its in-depth coverage of recent advances in radiation-induced signal transduction pathways and molecular mechanisms of cellular responses to ionizing radiation . . . succeeded in providing an up-to-date synopsis of the field of radiation research in the early 21st century and is a worthy addition to the library of didactic textbooks in our field. This book has a comprehensive and clearly laid out table of contents. The text is succinct and easy to read. This book certainly belongs on the bookshelf of anyone who is interested in understanding radiation biology including residents, graduate students, and postdoctoral researchers. In particular, radiation oncology residents will find this book to be an excellent source of information for understanding the molecular basis of radiation biology. - Zhong Yun and Joann B. Sweasy, Department of Therapeutic Radiology, Yale University School of Medicine, 2009 . . . this progressive text offers an up-to-date analysis of in vitro and in vivo molecular responses in the body induced by ionizing radiation. With a unique emphasis on medical physics applications, this volume also presents a much needed, in-depth perspective on clinical applications for the treatment of cancer and radiation injuries . . . an outstanding resource for advanced undergraduate and graduate students in medical physics, radiation oncology, radiation biology, and those who have an interest in the radiation sciences and in cancer treatment. -In Anticancer Research, Nov-Dec 2008, Vol. 28, No. 6B