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Biological Implications of Circadian Disruption

A Modern Health Challenge

Laura K. Fonken (University of Texas, Austin) Randy J. Nelson (West Virginia University)

$150.95

Hardback

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English
Cambridge University Press
12 October 2023
Life on earth has evolved under a consistent cycle of light and darkness caused by the earth's rotation around its axis. This has led to a 24-hour circadian system in most organisms, ranging all the way from fungi to humans. With the advent of electric light in the 19th century, cycles of light and darkness have drastically changed. Shift workers and others exposed to high levels of light at night are at increased risk of health problems, including metabolic syndrome, depression, sleep disorders, dementia, heart disease, and cancer. This book will describe how the circadian system regulates physiology and behavior and consider the important health repercussions of chronic disruption of the circadian system in our increasingly lit world. The research summarized here will interest students in psychology, biology, neuroscience, immunology, medicine, and ecology.

Edited by:   ,
Imprint:   Cambridge University Press
Country of Publication:   United Kingdom
Weight:   923g
ISBN:   9781316512081
ISBN 10:   1316512088
Pages:   360
Publication Date:  
Audience:   General/trade ,  ELT Advanced
Format:   Hardback
Publisher's Status:   Active
1. Introduction to circadian rhythms Laura K. Fonken and Randy J. Nelson; 2. Central clock dynamics: daily timekeeping, photic processing, and photoperiodic encoding by the suprachiasmatic nucleus Deborah A. M. Joye, Robert Wheeler and Jennifer A. Evans; 3. Melatonin, light, and the circadian system Margarita L. Dubocovich; 4. Disrupted circadian rhythms, stress, and allostatic load Ilia N. Karatsoreos; 5. Disrupted circadian rhythms and mental health Anthony Rosenthal and Tara A. LeGates; 6. Circadian rhythms and cognitive functioning Jacob S. Moeller and Lance J. Kriegsfeld; 7. Circadian rhythm disruption in aging and Alzheimer's disease Marilyn J. Duncan; 8. Circadian rhythms regulate neuroinflammation after traumatic brain injury and spinal cord injury Andrew D. Gaudet and Emily K. Greenough; 9. Disrupted circadian rhythms and neuroendocrine function in fertility Alexandra M. Yaw, Brooke M. DeVries and Hanne M. Hoffmann; 10. Disrupted circadian rhythms and metabolic function Deanna M. Arble; 11. Disrupted circadian rhythms, time restricted feeding, and blood pressure regulation Zhenheng Guo, Tianfei Hou and Ming C. Gong; 12. Disrupted circadian rhythms and immune function Louise M. Ince, Devin Simpkins and Julie E. Gibbs; 13. Circadian rhythms and cardiac function Leandro C. Brito, Saurabh S. Thosar, and Matthew P. Butler; 14. Disrupted circadian rhythms and cancer Baharan Fekry and Kristin Eckel-Mahan; 15. Light effects across species in nature: a focus on solutions Kevin J. Gaston and Johanna H. Meijer; 16. Measurement and analysis of exposure to light at night in epidemiology Xiaozhe Yin and Travis Longcore.

Dr. Laura K. Fonken is an Assistant Professor at the University of Texas Austin, USA. She earned her BS in Biology and Psychology from Syracuse University before completing a Ph.D. in Neuroscience at The Ohio State University in 2013. She has published over sixty academic papers and reviews, twenty of which are focused on circadian regulation of physiology and behavior. She was awarded the Society for Behavioral Neuroendocrinology Frank A. Beach Early Career Award and the Texas Society for Circadian Biology and Medicine Ron Konopka Junior Faculty Award. Dr. Randy J. Nelson is Professor and Inaugural Chair of the Department of Neuroscience at West Virginia University, USA. He holds the Hazel Ruby McQuain Chair for Neurological Research. He also directs the WVU Center for Foundational Neuroscience Research and Education, and the foundational science program for the Rockefeller Neuroscience Institute. He earned his AB and MA degrees in Psychology from the University of California at Berkeley, USA, before completing a Ph.D. in Psychology and a Ph.D. in Endocrinology. He has authored and edited ten books, including An Introduction to Behavioral Endocrinology (6th edition, 2022).

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