Axon Regrowth: The Neurobiology of Nerve and Axon Regeneration

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Douglas W Zochodne, MD, FRCPC (Neurologist and Neuroscientist, Director of the Neuroscience and Mental Health Institute, University of Alberta, Alberta, Canada)

Axon Regrowth

The Neurobiology of Nerve and Axon Regeneration

Douglas W Zochodne, MD, FRCPC (Neurologist and Neuroscientist, Director of the Neuroscience and Mental Health Institute, University of Alberta, Alberta, Canada)

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English

Academic Press Inc
01 December 2025

Neurology & clinical neurophysiology; Neurosciences

In the second edition of Axon Regrowth: The Neurobiology of Nerve and Axon Regeneration, this comprehensive volume explores the intricate processes of nerve and axon regeneration, addressing one of the most prevalent challenges in neurology. Building on the foundation of the original 2008 publication, this revised edition includes critical new chapters on central nervous system axon regeneration and nerve repair, highlighting both the similarities and differences in regenerative mechanisms between peripheral and central neurons. The book offers an in-depth examination of topics such as axonal degeneration, the biology of Schwann cells, and the role of growth factors and intrinsic signaling pathways. It also discusses the complexities of delayed reinnervation and the potential of dorsal root ganglia and ganglion stem cells in therapeutic approaches. By evaluating experimental neuropathies, this resource provides valuable insights for researchers and clinicians striving to develop effective strategies for nerve repair. With its meticulous review of molecular mechanisms and experimental methodologies, this edition serves as an essential guide for understanding and addressing the challenges of nerve regeneration.

By: Douglas W Zochodne MD FRCPC (Neurologist and Neuroscientist Director of the Neuroscience and Mental Health Institute University of Alberta Alberta Canada)
Imprint: Academic Press Inc
Country of Publication: United States
Dimensions: Height: 235mm, Width: 191mm,
Weight: 450g
ISBN: 9780443220654
ISBN 10: 0443220654
Pages: 394
Publication Date: 01 December 2025
Audience: Professional and scholarly , College/higher education , Undergraduate , Further / Higher Education
Format: Paperback
Publisher's Status: Active

Dr. Douglas Zochodne is a Neurologist and Neuroscientist, Director of the Neuroscience and Mental Health Institute, and Past Divisional Director of Neurology at the University of Alberta (UofA). Dr. Zochodne’s career has included faculty positions at Queen’s University, Canada, the University of Calgary and more recently the University of Alberta. Dr. Zochodne’s roles have included Editor-in-Chief of the Canadian Journal of Neurological Sciences, and President of the Peripheral Nerve Society. He is a Fellow of the Canadian Academy of Health Sciences and his book “Our Wired Nerves: The Human Nerve Connectome was published in 2020. He has devoted his career toward understanding the biology and diseases of the peripheral nervous system.