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Autophagy and Signaling

Esther Wong

$315

Hardback

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English
CRC Press Inc
14 September 2017
Autophagy and Signaling is an up-to-date overview of the many signaling pathways regulating autophagy in response to different cellular needs. Discussion includes the status and future directions of autophagy signaling research with respect to different aspects of health and disease. These include the roles of autophagy in regulating cell fate, immune response and host defense, nutrient sensing and metabolism, neural functions and homeostasis. The mechanisms and significance of cross-talk between autophagy and other cellular processes is also explored. Lastly, alterations in autophagy observed in aging and age-related pathologies are described.

Edited by:  
Imprint:   CRC Press Inc
Country of Publication:   United States
Dimensions:   Height: 234mm,  Width: 156mm, 
Weight:   589g
ISBN:   9781498731898
ISBN 10:   1498731899
Series:   Methods in Signal Transduction Series
Pages:   268
Publication Date:  
Audience:   General/trade ,  College/higher education ,  Professional and scholarly ,  ELT Advanced ,  Primary
Format:   Hardback
Publisher's Status:   Active

Esther Wong graduated from the National University of Singapore with her PhD in 2004. She is an Assistant Professor with the School of Biological Sciences at Nanyang Technological University in Singapore. Her research focuses on autophagy, a cellular quality control pathway involved in protein degradation by lysosomes. The overall goal is to elucidate yet unknown mechanisms in the degradation of proteins by autophagy and how the related defects result in accumulation of damaged components, proteotoxicity and loss of cognitive functions associated with neurodegeneration and aging.

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