From the reviews: <p>STATISTICAL METHODS IN MEDICAL RESEARCH AN INTERNATIONAL REVIEW JOURNAL <p>.,. this book is extremely good and highly recommended to statisticians involved in the drug development process. <p> The book has a dual purpose. First, it contains examples of statistics in practice and includes interesting real-life examples a ] . The second purpose of the book is to promote the use of S-Plus, by showing what can be done with this software, and illustrating its use a ] . this is a very valuable book of case studies. Managers of Biometrics groups should ensure their staff have access to a copy and statistics consultants will need a copy of their own. (Tim Auton, Journal of Applied Statistics, Vol. 30 (1), 2003) <p> Most of the chapters are written from a procedural perspective, describing the task to be done, showing the S-PLUS code required to conduct the task, and then displaying the S-PLUS results. a ] For a reader already sold on S-PLUS and looking for ways to apply it in his or her work, this book will be appealing. a ] The book will help pharmaceutical statisticians implement S-PLUS in their work if they are new to S-PLUS. (Brian J. Eastwood, Journal of the American Statistical Association, Issue March, 2003) <p> Each one of the chapters begins with a short introduction to the subject, followed by background information on each source of data. ... and finishes with related references and an appendix with S-PLUS code. The latter is of major benefit to readers. It is very clearly set out with macros that cover a wide range of graphics and aspects of statistical analysis. a ] this book is extremely good and highly recommended to statisticians involved in the drugdevelopment process. (Vasilis Nikolaou, Statistical Methods in Medical Research, Vol. 11 (2), 2002)