From the reviews of the third edition: It is a compilation of papers summarizing the physiologic foundation of critical care medicine. Practitioners or senior trainees are an appropriate audience for this collection of papers written by world experts and selected by editors of the journal. ... This volume reflects many of the technical developments in critical care over the past decade. The editors have selected papers for importance and clarity of presentation. This is an excellent reference for practitioners needing guidance in critical care physiology and treatment strategies for difficult problems. (David J. Dries, Doody's Review Service, October, 2012)