Immunotherapy in Translational Cancer Research

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Laurence J. N. Cooper (Associate Professor, Pediatrics, University of Texas MD Anderson Cancer Center, Houston, TX, USA) Elizabeth A. Mittendorf (Professor, Department of Breast Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA)

Immunotherapy in Translational Cancer Research

Laurence J. N. Cooper (Associate Professor, Pediatrics, University of Texas MD Anderson Cancer Center, Houston, TX, USA), Elizabeth A. Mittendorf (Professor, Department of Breast Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA), Judy Moyes (Department of Pediatric Research, The University of Texas MD Anderson Cancer Center, Houston, TX, USA) , Sabitha Prabhakaran (Clinical Research Scientist, Department of Breast Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA)

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English

Wiley-Blackwell
13 April 2018

Chemotherapy

Series: Translational Oncology

A guide to state-of-the-art cancer immunotherapy in translational cancer research

A volume in the Translational Oncology series, Immunotherapy in Translational Cancer Research explores the recent developments in the role that immunotherapy plays in the treatment of a wide range of cancers. The editors present key concepts, illustrative examples, and suggest alternative strategies in order to achieve individualized targeted therapy. Comprehensive in scope, Immunotherapy in Translational Cancer Research reviews the relevant history, current state, and the future of burgeoning cancer-fighting therapies. The book also includes critical information on drug development, clinical trials, and governmental resources and regulatory issues.

Each chapter is created to feature: development of the immunotherapy; challenges that have been overcome in order to scale up and undertake clinical trials; and clinical experience and application of research. This authoritative volume is edited by a team of noted experts from MD Anderson Cancer Center, the world’s foremost cancer research and care center and:

Offers a comprehensive presentation of state-of-the-art cancer immunotherapy research that accelerates the pace of clinical cancer care Filled with the concepts, examples, and approaches for developing individualized therapy Explores the breath of treatments that reflect the complexity of the immune system itself Includes contributions from a panel international experts in the field of immunotherapy

Designed for physicians, medical students, scientists, pharmaceutical executives, public health and public policy government leaders and community oncologists, this essential resource offers a guide to the bidirectional interaction between laboratory and clinic immunotherapy cancer research.

Edited by: Laurence J. N. Cooper (Associate Professor Pediatrics University of Texas MD Anderson Cancer Center Houston TX USA), Elizabeth A. Mittendorf (Professor, Department of Breast Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA), Judy Moyes (Department of Pediatric Research, The University of Texas MD Anderson Cancer Center, Houston, TX, USA), Sabitha Prabhakaran (Clinical Research Scientist, Department of Breast Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA)
Imprint: Wiley-Blackwell
Country of Publication: United Kingdom
Dimensions: Height: 257mm, Width: 183mm, Spine: 18mm
Weight: 816g
ISBN: 9781118123225
ISBN 10: 1118123220
Series: Translational Oncology
Pages: 312
Publication Date: 13 April 2018
Audience: Professional and scholarly , Undergraduate
Format: Hardback
Publisher's Status: Active

Editors vi Contributors vii Introduction ix 1 Translation in Immunology: The Role of Translational Biomarkers to Guide Clinical Use of Immunotherapy for Cancer 1 Saranya Chumsri and Keith L. Knutson 2 Monoclonal Antibody Therapy 12 Elizabeth A. Mittendorf and Sabitha Prabhakaran 3 Somatic Mutations and Immunotherapy 24 Eric Tran 4 Checkpoint Blockade 37 Tracy A. Proverbs‐Singh Jedd Wolchok and Alexandra Snyder 5 Myeloid Leukemia Vaccines 54 Paul M. Armistead and Jonathan S. Serody 6 Cancer Vaccines for Solid Tumors 72 Timothy J. Vreeland Garth S. Herbert and George E. Peoples 7 Immunotherapy with Non–Genetically Modified T Cells 91 Cassian Yee 8 Immunotherapy with Genetically Modified T Cells 101 Liora Schultz and Crystal Mackall 9 Immunomodulation with Adjuvants and Cytokines 115 Dae won Kim and Adi Diab 10 Immune Cell Migration in Cancer and Immunotherapy 132 Timothy Murray and Daniel E. Speiser 11 Repurposing of Drugs for Immunotherapy 143 Jyothishmathi Swaminathan and Vidya Gopalakrishnan 12 Immunomodulation with Radiation 161 Jonathan E. Schoenhals Taylor R. Cushman, Alexandra P. Cadena Sandra Demaria and James W. Welsh 13 Good Manufacturing Practices Facilities for Cellular Therapy 177 Andrew D. Fesnak and Bruce L. Levine 14 T Cell Receptor Mimic Antibodies 186 Gheath Alatrash and Jeffrey J. Molldrem 15 Stem Cell Transplantation for Treatment of Malignancy 201 Lohith S. Bachegowda and Richard E. Champlin 16 Natural Killer Cell–Based Immunotherapy 215 Jennifer A. Foltz Jeffrey S. Miller and Dean A. Lee 17 Immunologic Monitoring in Immuno‐Oncology 228 William R. Gwin and Mary L. Disis 18 Cell‐Based Therapies for Canine Cancer 252 Nicola J. Mason and M. Kazim Panjwani 19 Interaction between Targeted Therapy and Immunotherapy 268 Peter A. Prieto Miles C. Andrews, Alexandria P. Cogdill, and Jennifer A. Wargo Index 286

Laurence J. N. Cooper, Associate Professor, Department of Pediatrics, The University of Texas MD Anderson Cancer Center, Houston, USA. Elizabeth A. Mittendorf, Professor, Department of Breast Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, USA. Judy Moyes, Department of Pediatric Research, The University of Texas MD Anderson Cancer Center, Houston, USA. Sabitha Prabhakaran, Clinical Research Scientist, Department of Breast Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, USA.

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Immunotherapy in Translational Cancer Research

$356.95

Hardback

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