Apoptosis: The molecular biology of programmed cell death

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Michael Jacobson (Millennium Pharmaceuticals Inc., Cambridge, MA, USA) Nicola McCarthy (Division of Cardiovascular Medicine, Addenbrookes Hospital, Cambridge, UK)

Apoptosis

The molecular biology of programmed cell death

Michael Jacobson (Millennium Pharmaceuticals Inc., Cambridge, MA, USA), Nicola McCarthy (Division of Cardiovascular Medicine, Addenbrookes Hospital, Cambridge, UK), Nicola McCarthy (Division of Cardiovascular Medicine, Addenbrookes Hospital, Cambridge)

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English

Oxford University Press
11 April 2002

Cellular physiology; Oncology; Biochemistry; Molecular biology; Cellular biology (cytology)

Series: Frontiers in Molecular Biology

Apoptosis is a regulated form of cell demise that can be induced or blocked by groups of specific stimuli. Occurring in all living tissues, it is thought critical to the maintenance of homeostasis and is implicated in lowering susceptibility to tumour growth. Conversely, over-sensitivity to apoptotic triggers can cause cells to be lost inappropriately from tissues, as appears to occur in neurodegenerative diseases. This book examines the molecular pathways regulating apoptosis, progressing from the nematode worm through Drosphila to the more complex pathways evident in mammalian cells. Differences in the cell death pathway within specific tissues are addressed, as are the different genes that may act to regulate progressive steps.

Edited by: Michael Jacobson (Millennium Pharmaceuticals Inc. Cambridge MA USA), Nicola McCarthy (Division of Cardiovascular Medicine, Addenbrookes Hospital, Cambridge, UK), Nicola McCarthy (Division of Cardiovascular Medicine, Addenbrookes Hospital, Cambridge)
Imprint: Oxford University Press
Country of Publication: United Kingdom
Volume: 40
Dimensions: Height: 245mm, Width: 190mm, Spine: 13mm
Weight: 791g
ISBN: 9780199638499
ISBN 10: 0199638497
Series: Frontiers in Molecular Biology
Pages: 346
Publication Date: 11 April 2002
Audience: Professional and scholarly , Undergraduate
Format: Paperback
Publisher's Status: Out of Print

Reviews for Apoptosis: The molecular biology of programmed cell death

The book is, essentially, a series of reviews of a quality you would expect to find in the top scientific journals. Not only will it prove a good introduction to researchers new to the field, it provides a very useful reference guide to those of us who are not specialists in PCD, but upon whose work the subject often impinges. Journal of Biological Education All the subjects are addressed at just the right level of complexity, with the emphasis on molecular processes involved ... four excellent colour plates. Journal of Biological Education