This detailed volume provides a single, valuable reference source for methods that definitively identify and accurately quantify apoptosis. The book begins with common methods utilized to detect and quantitate apoptosis, as well as apoptosis signaling pathways in toxicological and other related research. It continues with multi-parametric and phased apoptosis assays for detecting early and late apoptosis or distinguishing apoptosis from necrosis and autophagy. Subsequent chapters focus on recent advances in real time and high-throughput assays that detect and quantitate apoptosis and apoptosis signaling pathways. Final chapters focus on recent developments in preclinical anticancer therapeutics targeting apoptosis. Written for the Methods in Pharmacology and Toxicology series, chapters feature step-by-step descriptions of the methodologies, as well as expert tips and implementation advice.
Vital and authoritative, Apoptosis Methods in Toxicology serves novice scientists as well as experts, utilizing a range of instruments from common laboratory equipment to high-end expensive and automated machinery capable of performing real time apoptotic measurements.
Edited by:
Perpetua M. Muganda Imprint: Humana Press Inc. Country of Publication: United States Edition: Softcover reprint of the original 1st ed. 2016 Dimensions:
Height: 254mm,
Width: 178mm,
Spine: 14mm
Weight: 493g ISBN:9781493980864 ISBN 10: 1493980866 Series:Methods in Pharmacology and Toxicology Pages: 244 Publication Date:19 April 2018 Audience:
Professional and scholarly
,
Undergraduate
Format:Paperback Publisher's Status: Active