Antiphospholipid Antibody Syndrome

From Bench to Bedside

Pier Luigi Meroni

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Hardback

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English

Springer International Publishing AG
03 December 2014

Haematology; Rheumatology; Gynaecology & obstetrics

Series: Rare Diseases of the Immune System

This book, part of the series Rare Diseases of the Immune System, offers comprehensive, up-to-date coverage of the pathophysiology and management of the antiphospholipid syndrome (APS). Immunologic and genetic aspects are discussed and the pathogenic mechanisms responsible for such phenomena as APS-mediated thrombosis and pregnancy loss/complications are explained. The main clinical manifestations, classification criteria and diagnostic tools are identified, and close attention is paid to the nature of the involvement of various organs or organ systems in APS. Specific chapters describe the treatment of the different symptoms, therapies of value in avoiding recurrences, and innovative treatment approaches. The authors are senior experts in the field who are aided by younger fellows, ensuring that the book is also educationally oriented. This handy volume will be a valuable tool for postgraduates in training and professionals wishing to extend their knowledge of this specific syndrome.

Edited by: Pier Luigi Meroni
Imprint: Springer International Publishing AG
Country of Publication: Switzerland
Edition: 2015 ed.
Dimensions: Height: 235mm, Width: 155mm, Spine: 18mm
Weight: 604g
ISBN: 9783319110431
ISBN 10: 3319110438
Series: Rare Diseases of the Immune System
Pages: 267
Publication Date: 03 December 2014
Audience: Professional and scholarly , Undergraduate
Format: Hardback
Publisher's Status: Active

Foreword.- Preface.- 1 APS: Introductory notes.- 2 Immunology and Genetics of APS.- 3 The paradox of the lupus anticoagulant.- 4 The pathogenic mechanism(s) for APS-mediated thrombosis.- 5 The pathogenic mechanism(s) for APS-mediated pregnancy loss.- 6 Classification criteria.- 7 Non-classification criteria.- 8 Obstetric APS.- 9 APS and the nervous system.- 10 APS and renal involvement.- 11 Non-thrombotic hematologic manifestations in APS.- 12 Heart and APS.- 13 Skin and APS.- 14 Additional organs involved in APS (eye, ENT, GI, endocrine).- 15 Treatment of thrombosis.- 16 Treatment of pregnancy complications.- 17 Asymptomatic carries of APS.- 18 New treatments.- 19 Secondary APS.- 20 Catastrophic APS.

Reviews for Antiphospholipid Antibody Syndrome: From Bench to Bedside

From the book reviews: “The purpose is to provide an overview of this very difficult subject that will benefit bench researchers as well as bedside clinicians. The book would serve any audience who wants to know more about antiphospholipid syndrome. … This is an excellent, up-to-date overview of antiphospholipid syndrome. It will serve as a handy tool to get more information on the topic.” (Dany V. Thekkemuriyil, Doody’s Book Reviews, February, 2015)