Antibiotics

Name: Antibiotics
Price: 257.95 AUD
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ISBN: 9781683674887

Challenges, Mechanisms, Opportunities

Timothy Wencewicz (Washington University in St. Louis)

$257.95

Hardback

Forthcoming
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English

American Society for Microbiology
05 June 2026

Biochemical engineering

Series: ASM Books

Summary
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A chemocentric view of the molecular structures of antibiotics, their origins, actions, and major categories of resistance

Antibiotics: Challenges, Mechanisms, Opportunities focuses on antibiotics as small organic molecules, from both natural and synthetic sources. Understanding the chemical scaffold and functional group structures of the major classes of clinically useful antibiotics is critical to understanding how antibiotics interact selectively with bacterial targets.

This textbook details how classes of antibiotics interact with five known robust bacterial targets: cell wall assembly and maintenance, membrane integrity, protein synthesis, DNA and RNA information transfer, and the folate pathway to deoxythymidylate. It also addresses the universe of bacterial resistance, from the concept of the resistome to the three major mechanisms of resistance: antibiotic destruction, antibiotic active efflux, and alteration of antibiotic targets. Antibiotics also covers the biosynthetic machinery for the major classes of natural product antibiotics.

Authors Christopher Walsh and Timothy Wencewicz provide compelling answers to these questions:

What are antibiotics? Where do antibiotics come from? How do antibiotics work? Why do antibiotics stop working? How should our limited inventory of effective antibiotics be addressed?

Antibiotics is a textbook for graduate courses in chemical biology, pharmacology, medicinal chemistry, and microbiology and biochemistry courses. It is also a valuable reference for microbiologists, biological and natural product chemists, pharmacologists, and research and development scientists.

By: Timothy Wencewicz (Washington University in St. Louis)
Imprint: American Society for Microbiology
Country of Publication: United States
Edition: 3rd Revised edition
ISBN: 9781683674887
ISBN 10: 168367488X
Series: ASM Books
Pages: 512
Publication Date: 05 June 2026
Audience: Professional and scholarly , Undergraduate
Format: Hardback
Publisher's Status: Forthcoming