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English
Academic Press Inc
23 July 2013
Animal Models for the Study of Human Disease identifies important animal models and assesses the advantages and disadvantages of each model for the study of human disease. The first section addresses how to locate resources, animal alternatives, animal ethics and related issues, much needed information for researchers across the biological sciences and biomedicine.

The next sections of the work offers models for disease-oriented topics, including cardiac and pulmonary diseases, aging, infectious diseases, obesity, diabetes, neurological diseases, joint diseases, visual disorders, cancer, hypertension, genetic diseases, and diseases of abuse.

Edited by:   ,
Imprint:   Academic Press Inc
Country of Publication:   United States
Dimensions:   Height: 276mm,  Width: 215mm,  Spine: 53mm
Weight:   3.270kg
ISBN:   9780124158948
ISBN 10:   0124158943
Pages:   1108
Publication Date:  
Audience:   Professional and scholarly ,  Undergraduate
Replaced By:   9780128094686
Format:   Hardback
Publisher's Status:   Active
Preface Section A. ETHICS, RESOURCES AND APPROACHES Section B. VISION Section C. CARDIAC AND CARDIOVASCULAR Section D. OBESITY, METABOLIC AND LIVER Section E. BONE AND SKIN Section F. URINARY TRACT, KIDNEY AND BOWEL Section G. THE BRAIN, STROKE, AND NEUROMUSCULAR Section H. BEHAVIOR Section I. GENETICS Section J. EARLY LIFE Section K. VIRAL DISEASE Section L. CANCER Section M. SCLEROSIS

P. Michael Conn is the Senior Vice President for Research and Associate Provost, Texas Tech Health Sciences Center. He was previously Director of Research Advocacy and Professor of Physiology and Pharmacology, Cell Biology and Development and Obstetrics and Gynecology at Oregon Health and Science University and Senior Scientist of the Oregon National Primate Research Center (ONPRC). He served for twelve years as Special Assistant to the President and Associate Director of the ONPRC. After receiving a B.S. degree and teaching certification from the University of Michigan (1971), a M.S. from North Carolina State University (1973), and a Ph.D. degree from Baylor College of Medicine (1976), Conn did a fellowship at the NIH, then joined the faculty in the Department of Pharmacology, Duke University Medical Center where he was promoted to Associate Professor in 1982. In 1984, he became Professor and Head of Pharmacology at the University of Iowa College of Medicine, a position he held for eleven years. Conn is known for his research in the area of the cellular and molecular basis of action of gonadotropin releasing hormone action in the pituitary and therapeutic approaches that restore misfolded proteins to function. His work has led to drugs that have benefitted humans and animals. He has authored or co-authored over 350 publications in this area and written or edited over 200 books, including texts in neurosciences, molecular biology and endocrinology. Conn has served as the editor of many professional journals and book series (Endocrinology, Journal of Clinical Endocrinology and Metabolism, Endocrine, Methods, Progress in Molecular Biology and Translational Science and Contemporary Endocrinology). Conn served on the National Board of Medical Examiners, including two years as chairman of the reproduction and endocrinology committee. The work of his laboratory has been recognized with a MERIT award from the NIH, the J.J. Abel Award of the American Society for Pharmacology and Experimental Therapeutics, the Weitzman, Oppenheimer and Ingbar Awards of the Endocrine Society, the National Science Medal of Mexico (the Miguel Aleman Prize) and the Stevenson Award of Canada. He is the recipient of the Oregon State Award for Discovery, the Media Award of the American College of Neuropsychopharmacology and was named a distinguished Alumnus of Baylor College of Medicine in 2012. He is an elected member of the Mexican Institute of Medicine and a fellow of the American Association for the Advancement of Science.

Reviews for Animal Models for the Study of Human Disease

"""...addresses how to locate resources, animal alternatives, animal ethics and related issues, much needed information for researchers across the biological sciences and biomedicine."" --Anticancer Research, February 2015 ""…a very detailed textbook for researchers and laboratory animal veterinarians interested in getting an understanding of some of the animal models of human diseases.  The authors have done a good job of reviewing the numerous animal models in various physiological systems."" --Laboratory Animal Practitioner, June 2014 ""Conn presents this compendium on animal models in biomedical research, beginning with a section on ethical justifications, resources, and methodology to optimize the scientific value obtained from animal experiments. After this discussion, the volume is organized by disease group…The book aims to present successful animal models with the greatest homology to human systems."" --ProtoView.com, February 2014 ""This comprehensive textbook identifies important animal models and assesses the advantages and disadvantages of each model for the study of human disease…Organized by disease orientation for ease of searchability…Provides information on locating resources, animal alternatives and animal ethics."" --Anticancer Research, 34, 2014 ""…overall, the content (figures, tables and descriptions of the animal models and their significance) is excellent and should be considered a useful resource…Any laboratory animal research program, particularly those with an interest in working with multiple species of animal models, would benefit from having this book in the library."" --Lab Animal, February 2014"


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