Comprehensive guide offering actionable strategies for enhancing human-centered AI, efficiency, and productivity in industrial and systems engineering through the power of AI.
Advances in Artificial Intelligence Applications in Industrial and Systems Engineering is the first book in the Advances in Industrial and Systems Engineering series, offering insights into AI techniques, challenges, and applications across various industrial and systems engineering (ISE) domains. Not only does the book chart current AI trends and tools for effective integration, but it also raises pivotal ethical concerns and explores the latest methodologies, tools, and real-world examples relevant to today’s dynamic ISE landscape.
Readers will gain a practical toolkit for effective integration and utilization of AI in system design and operation. The book also presents the current state of AI across big data analytics, machine learning, artificial intelligence tools, cloud-based AI applications, neural-based technologies, modeling and simulation in the metaverse, intelligent systems engineering, and more, and discusses future trends.
Written by renowned international contributors for an international audience, Advances in Artificial Intelligence Applications in Industrial and Systems Engineering includes information on:
Reinforcement learning, computer vision and perception, and safety considerations for autonomous systems (AS) (NLP) topics including language understanding and generation, sentiment analysis and text classification, and machine translation AI in healthcare, covering medical imaging and diagnostics, drug discovery and personalized medicine, and patient monitoring and predictive analysis Cybersecurity, covering threat detection and intrusion prevention, fraud detection and risk management, and network security Social good applications including poverty alleviation and education, environmental sustainability, and disaster response and humanitarian aid.
Advances in Artificial Intelligence Applications in Industrial and Systems Engineering is a timely, essential reference for engineering, computer science, and business professionals worldwide.
About the Editors xxiii Preface xxv 1 Introduction to Industrial Artificial Intelligence 1 Dai-Yan Ji, Hanqi Su, Takanobu Minami, and Jay Lee, USA 1.1 Fundamental Problems in Industry 1 1.2 The Purpose of Industrial AI 2 1.3 Difference Between AI and Industrial AI 4 1.4 Definition and Meaning of Industrial AI 5 1.5 Key Elements in Industrial AI: ABCDE 7 1.6 CPS Framework for Industrial AI 8 1.7 Technological Elements of CPS Framework 9 1.8 Developing Industrial AI Talents 10 1.9 Training Industrial AI Talents Using Open-source Datasets 10 1.10 Issues in Industrial AI 14 1.11 Conclusion 16 References 17 2 Autonomous Systems and Intelligent Agents 19 Babak Ebrahimi Soorchaei, Arash Raftari, and Yaser Fallah, USA 2.1 Definitions and Scopes 19 2.1.1 What Are Autonomous Systems? 19 2.1.2 What Are Intelligent Agents? 20 2.1.3 Degrees of Autonomy: From Manual to Full Autonomy 20 2.1.4 Overview of Applications and Impact on Various Industries 21 2.2 Core Concepts and Components 21 2.2.1 Artificial Intelligence and Machine Learning 21 2.2.1.1 Basics of AI and ML 22 2.2.1.2 Role in Autonomous Systems 22 Table of Contents ftoc.indd 9 6/19/2025 2:48:48 PM x Table of Contents 2.2.2 Perception, Decision-making, and Action 22 2.2.2.1 Perception 22 2.2.2.2 Decision-making Processes, Planning, and Navigation 23 2.2.2.3 Actuation and Interaction with the Environment 24 2.2.3 Communication and Interaction 26 2.2.3.1 Agent Communication Languages and Protocols 26 2.2.3.2 Communication’s Role in Coordination and Cooperation and Challenges 26 2.3 Applications and Case Study: Autonomous Vehicle 27 2.3.1 System Architecture in AVs 27 2.3.1.1 Modular (Layered) Architecture 27 2.3.1.2 End-to-End Architecture 28 2.3.2 Perception in AVs 30 2.3.2.1 Sensing 30 2.3.2.2 Object Detection 30 2.3.2.3 Multi-object Tracking 31 2.3.2.4 Semantic Segmentation 32 2.3.2.5 Localization and Mapping 32 2.3.3 Planning and Decision-making 33 2.3.3.1 Path (Route) Planning 33 2.3.3.2 Behavior Planning 33 2.3.3.3 Motion (Trajectory) Planning 33 2.3.4 Control System, Actuation, and Interaction with the Environment 34 2.3.4.1 Lateral Control 34 2.3.4.2 Longitudinal Control 34 2.3.4.3 Actuators 35 2.3.5 Vehicular Communication and Cooperative Intelligence 35 2.3.5.1 Cooperative AI in Autonomous Driving 36 2.4 Challenges and Future Directions 37 References 38 3 Natural Language Processing for Industrial and Systems Engineering 43 Daniel Braun, Germany 3.1 Introduction 43 3.2 Advances and Trends in NLP 44 3.2.1 Large Language Model 44 3.2.2 Unsupervised Approaches 46 3.2.3 Knowledge Graphs 47 3.3 Domain-specific Challenges in ISE 47 3.3.1 Domain-specific Vocabulary 48 3.3.2 Multimodality 48 3.3.3 Complexity 49 3.3.4 Liability and Accountability 49 ftoc.indd 10 6/19/2025 2:48:48 PM Table of Contents xi 3.4 Applications of NLP in ISE 50 3.4.1 Technology Scouting 50 3.4.2 Analysis of Requirements Documents 51 3.4.3 Analysis of Regulatory and Legal Documents 51 3.4.4 Engineering Education 52 3.5 Outlook 52 3.5.1 Local Inference 53 3.5.2 Multimodality 53 3.5.3 Transparency 53 3.5.4 Retrieval-augmented Generation 53 3.5.5 Reinforcement Learning from Human Feedback 54 References 54 4 Smart Manufacturing, Robotics, and AI Systems 61 Xifan Yao, Huifeng Yan, Jiajun Zhou, Yongxiang Li, and Hongnian Yu, China/UK 4.1 Introduction to Smart Manufacturing 61 4.1.1 Evolution of Manufacturing Paradigms 61 4.1.2 Industry 4.0 62 4.1.3 Key Components of Smart Manufacturing/Industry 4.0 62 4.2 Smart Manufacturing System Integration and Interoperability 63 4.2.1 Smart Manufacturing Reference Model 63 4.2.2 Extended Smart Manufacturing System Integration and Interoperability 63 4.2.3 Cyber-physical Production Systems 64 4.2.4 Extended CPPS 65 4.2.4.1 Socio-Cyber-physical Production System 65 4.2.4.2 Autonomous Cyber-physical Production Systems 65 4.2.4.3 Human-centric CPPS 65 4.2.4.4 Metaverse CPPS 65 4.2.5 The Intersection of Robotics and AI in Manufacturing 65 4.3 Robotics in Manufacturing 67 4.3.1 The Rise of Robotics in Manufacturing 67 4.3.2 Cobots in Manufacturing 67 4.3.3 AGVs in Manufacturing 68 4.3.4 Chatbots in Design/Manufacturing 69 4.4 AI in Manufacturing 70 4.4.1 Integration of AI with Manufacturing Systems 70 4.4.2 ML Applications in Predictive Maintenance 71 4.4.3 ML Models in Quality Control 72 4.4.4 Optimizing Production Scheduling with AI Algorithms 73 Acknowledgments 74 References 75 ftoc.indd 11 6/19/2025 2:48:48 PM xii Table of Contents 5 Artificial Intelligence in Healthcare 79 Vinita Gangaram Jansari, USA 5.1 History of Artificial Intelligence in Healthcare 79 5.1.1 Challenges and Limitations 80 5.2 New Age of Healthcare with the Use of AI 81 5.2.1 Large Language Model for Healthcare Domain 81 5.2.2 Generative AI for Healthcare Domain 83 5.3 AI-enabled Medical Devices 85 5.4 Explainable AI for Healthcare 86 5.5 Medical Decision Support Systems 87 5.6 Precision/Personalized Medicine Using AI 88 5.7 Smart Healthcare 89 5.8 Healthcare 5.0 90 5.8.1 Remote Patient Monitoring 91 5.8.2 Assisted Surgery and Surgical Robots 91 5.8.3 Drug Design and Development 92 5.8.4 Assisted Living 93 5.8.5 Cancer Diagnostics and Treatment 94 5.9 Ethics, Bias, and Fairness Constraints 94 5.9.1 Addressing Ethics, Bias, and Fairness Constraints 95 5.10 Concluding Remarks 96 5.11 Future Directions 96 References 97 6 Artificial Intelligence in Cybersecurity for Industrial and Systems Engineering 111 Robin Yeman, Hasan Yasar, Suzette Johnson, and Tracy Bannon, USA 6.1 Introduction to Cybersecurity and Artificial Intelligence for Industrial and Systems Engineering 111 6.1.1 Application Areas 112 6.1.2 Challenges 113 6.2 Cyber Threat Landscape for CPS 113 6.3 AI in Cybersecurity for CPS 113 6.4 Risk Assessment, Compliance, and Regulatory Considerations 115 6.4.1 Risk Assessment 115 6.4.2 Compliance 115 6.4.3 Regulatory 116 6.5 Threat Detection and Prevention 116 6.5.1 Behavior Analysis 116 6.5.2 Threat Intelligence Integration 117 6.5.3 Security Information and Event Integration 117 6.5.4 Intrusion Detection System 117 6.5.5 Endpoint Detection and Response 117 ftoc.indd 12 6/19/2025 2:48:48 PM Table of Contents xiii 6.5.6 Log Analysis and Correlation 117 6.5.7 Network Traffic Analysis 118 6.5.8 Vulnerability Scanning and Assessment 118 6.6 Incident Response and Management 118 6.6.1 Preparation 118 6.6.2 Detect and Analyze 119 6.6.3 Contain, Eradicate, and Recover 119 6.6.4 Post-incident Recovery 120 6.7 Anti-phishing 120 6.8 Dependable Authentication 120 6.9 Behavior Analytics 121 6.10 Conclusion 121 References 122 7 Artificial Intelligence in Defense 125 Dylan Schmorrow, Robert Sottilare, Jack Zaientz, John Sauter, Randolph Jones, Charles Newton, Joseph Cohn, Jon Sussman-Fort, Robert Bixler, Brice Colby, Victor Hung, Jeffrey Craighead, Le Nguyen, and Ullice Pelican, USA 7.1 Introduction 125 7.2 Ethical Considerations and Challenges 126 7.2.1 Ethical Principles in Defense AI 126 7.2.2 Challenges in Ethical AI Deployment 127 7.2.3 Regulatory and Policy Frameworks 128 7.3 AI-driven Innovations in C2 Systems 129 7.3.1 Planning and COA Generation 130 7.3.1.1 Distributed Scheduling and Task Allocation 130 7.3.1.2 Reinforcement Learning 131 7.3.1.3 Large Language Models 131 7.3.2 Plan Monitoring and Risk Assessment 131 7.3.3 Object Detection and Classification 132 7.4 AI Applications in Uncrewed Systems 132 7.4.1 Military Applications and Benefits 132 7.4.2 AI Technologies in Support of Autonomy 133 7.4.3 Challenges and Future Directions 133 7.4.4 Conclusion 134 7.5 Application of AI to Cyber Operations 134 7.5.1 Representation of Cyber Tactics, Techniques, and Procedures 134 7.5.2 Cyber Attack AI Models 135 7.5.3 Cyber Defense AI Models 136 7.5.4 Cyber Social AI Models 136 7.6 AI-enabled Training and Simulation Systems 137 7.6.1 Training Preparation Process 138 ftoc.indd 13 6/19/2025 2:48:48 PM xiv Table of Contents 7.6.1.1 Curriculum Development 138 7.6.1.2 Skills Gap Analysis 138 7.6.1.3 Scheduling and Resource Optimization 138 7.6.2 Training Execution Process 139 7.6.2.1 Adaptive Learning 139 7.6.2.2 Simulation and Gamification 140 7.6.2.3 Intelligent Virtual Instructors and Virtual Entities 141 7.6.3 Training Review Process 141 7.6.3.1 Performance Analysis 142 7.6.3.2 Feedback Development 142 7.6.3.3 Interventions for Continuous Improvement 143 7.7 AI-enabled HMI Technologies 143 7.7.1 Intuitive User Interfaces 144 7.7.2 Personalized HMIs 144 7.7.3 Future Directions for Intuitive and Personalized HMIs 145 7.8 Integrating Machine Reasoning and Explanation for Dynamic Decision-making 146 7.9 Responsible AI in Predictive Systems and Medical/Defense Health Readiness 148 7.9.1 ELSI: A Framework for Responsible AI in Defense Healthcare 149 7.9.2 Context of Defense Healthcare Systems 149 7.9.3 Applying AI in Defense Health Systems 149 7.9.4 ELSI Considerations with AI in Defense Health Systems 149 7.9.5 Mitigations 150 7.9.6 Summary 150 7.10 Future Directions 150 7.10.1 Future Directions in C2 Systems 151 7.10.2 Future Directions in UxS 151 7.10.3 Future Directions in Cyber Operations 151 7.10.4 Future Directions in Training and Simulation 152 7.10.5 Future Directions in HMI Technologies 152 7.10.6 Future Directions in Machine Reasoning and Dynamic Decision-making 152 7.10.7 Future Directions in Defense Healthcare 153 7.10.8 Future Directions for the General Application of AI in Defense 153 7.11 Conclusion 154 References 154 8 AI-Driven Management and Modeling Decision Optimization as a Timely Opportunity at the US Department of Defense 159 Link Parikh, USA 8.1 Why Act Now and Why Engineering Lifecycle and AI? 159 8.1.1 The Global Driver for AI 159 8.1.2 Urgency 160 8.1.3 No Math Gets Us “There” with What We Have Today 160 ftoc.indd 14 6/19/2025 2:48:48 PM Table of Contents xv 8.1.4 DoD Program-level Challenges 161 8.1.5 Realization and Subsequent Brave Decision by NASA to Outsource Low Earth Orbit Launch 162 8.1.6 The Automotive Industry 162 8.1.7 What Are the Consequences of Inaction? 162 8.1.8 Culture, Mindset, or Perspective? 162 8.1.9 Beyond the United States 162 8.2 Who Needs to Make Changes in the Ecosystem? 163 8.2.1 Key Participants in Decision Support and Optimization 164 8.2.2 Upgrading DoD Management and Operations to Meet the Needs of AI Injection 165 8.2.3 AI Lifecycle Management 165 8.2.4 Solving the Classified Data Problem with a Data Fabric 166 8.2.5 Sample Application: AI Autonomy 166 8.2.6 AI and Change Management 167 8.3 How to Implement the AI-driven Ecosystems Management and Modeling Regime 167 8.3.1 PPTI Framework Has Assisted Executives for Decades 167 8.3.2 Solutions Based on Insights from the Field 167 8.4 Key Elements of AI-driven Ecosystem Management and Modeling 169 8.4.1 We Must Integrate Program Management and Systems Engineering 170 8.4.2 Harmonize Agile Development with Traditional Acquisition 171 8.4.3 Ensure Requirements Quality for Testable Language 172 8.4.4 Increase Concurrency in Simulation and Training 172 8.4.5 Enhance Cybersecurity with MBSE 173 8.4.6 Embed Human Factors into MBSE 173 8.4.7 Implement Early End-user Participation 173 8.4.8 Prioritize Sustainment Planning from Program Start 173 8.4.9 Understand and Utilize “V and V” and “IV and V” 174 8.4.10 Enable Impact Analysis for All 174 8.4.11 Conduct Rigorous Prototyping Projects with Top Experts 175 8.4.12 Engage Small Businesses in Ideation Diversity: Neuro Diversity 176 8.4.13 Implement Virtual and Augmented Reality (VR/AR) and Metaverse Tools in Program Engineering 176 8.4.14 Accelerate Source Selection with Remote, Model-based Capabilities 176 8.4.15 Use Integrated, Model-based Compliance 176 8.4.16 Fully Integrate AI Management into the Total Lifecycle 176 8.4.17 NLP and Pretrained COTS Models 176 8.4.18 Machine Learning 177 8.4.19 Deep Learning (DL) and Neural Networks 177 8.4.20 AI Model Accelerators 177 8.4.21 Generative AI Concepts 177 8.4.22 Implement Digital Twins with Digital Threads 177 8.4.23 Leverage Quantum Computing 177 ftoc.indd 15 6/19/2025 2:48:48 PM xvi Table of Contents 8.4.24 Implement a Data Fabric 178 8.5 Enhance Workforce Development and Mentorship 178 8.5.1 Layer 1: Domain Knowledge 178 8.5.2 Layer 2: Practice Knowledge 178 8.5.3 Layer 3: Tools and Platforms 178 8.5.4 Layer 4: Techniques 179 8.6 When Can We Acquire Dramatic Speed and Precision? 179 8.7 Which Elements Exist in “AI Ecosystem Management and Modeling?” 179 8.7.1 Integrated Object-oriented Model(s) 179 8.7.2 Integrated Modeling with the Right Profile, UAFML 180 8.7.3 Integrated Engineering Lifecycle Platform Foundation 181 8.7.4 Integrated Justifications That Drive Requirements Generation and Traceability 181 8.7.5 Integrated Program Method for Standardization, Improvement, and Business Continuity 182 8.7.6 Integrated Requirements Generation, Traceability, Management 182 8.7.7 Integrated Requirements Quality Scanner 183 8.7.8 Integrated Portfolio/Project Management and Workflow Management 183 8.7.9 Integrated Change Management 183 8.7.10 Integrated “Commenting” on Program Assets by Stakeholders, Performers (and AI Agents) 184 8.7.11 Integrated Software Build Automation and Continuous Integration/Delivery 184 8.7.12 Integrated Testing, “V and V,” and “IV and V” 185 8.7.13 Integrated Communities of Interest 185 8.7.14 Integrated Automated Publishing 186 8.7.15 Integrated AI Governance Platform 186 8.7.16 Integrated Insights from Program and External Data 187 8.7.17 Integrated ML for Predictivity 188 8.7.18 Integrated DL for Answers and Options to Achieve Decision Optimization 188 8.7.19 Generative AI 188 8.7.20 AI Autonomy 189 8.7.21 Should We Ban All Research on Conscious AI Research? 190 8.8 Sample Applications of Dramatic Speed and Precision 191 8.8.1 Model-based Acquisition and Source Selection 191 8.8.2 Innovation Process from Ideation to Program Injection and DOTMLPF Entry 191 8.8.3 Integrated Ideation 191 8.8.4 Integrated Software Development and Continuous Integration/Delivery 192 8.8.5 Physical Simulation and Digital Twin 192 8.8.6 Capability Summary 192 8.9 AI-driven Ecosystem Management and Modeling Solution and Toolset 192 8.9.1 Foundational Concepts and Canonical View 192 8.9.2 Solution Elements and Platform Architecture 193 8.9.3 Solution Capabilities and Tools 194 8.10 Summary 194 ftoc.indd 16 6/19/2025 2:48:48 PM Table of Contents xvii 9 Enhancing Cryptocurrency Market Forecasting: Advanced Machine Learning Techniques and Industrial Engineering Contributions 197 Jannatun Nayeem Pinky and Ramya Akula, USA 9.1 Introduction 197 9.2 Background 199 9.3 Methods 201 9.3.1 Linear Models 201 9.3.1.1 Linear Regression 202 9.3.1.2 Bayesian Ridge Regression 203 9.3.1.3 Support Vector Machine 204 9.3.1.4 Linear Discriminant Analysis 205 9.3.1.5 Multiple Linear Regression 206 9.3.1.6 Logistic Regression 206 9.3.2 Tree-based Models 207 9.3.2.1 Random Forest 208 9.3.2.2 Gradient Boosting 209 9.3.2.3 XGBoost 209 9.3.2.4 LightGBM 210 9.3.3 Probabilistic and Clustering Models 210 9.3.3.1 Naïve Bayes 211 9.3.3.2 Latent Dirichlet Allocation 212 9.3.4 Deep Learning Algorithms 212 9.3.4.1 Multilayer Perceptron 213 9.3.4.2 Long Short-term Memory 214 9.3.4.3 Gated Recurrent Unit 214 9.3.4.4 Bidirectional LSTM 215 9.3.4.5 Bidirectional CNN-RNN Architecture (CGWELSTM) 216 9.3.4.6 DL-GuesS: System Model 218 9.3.4.7 AT-LSTM-MLP Model 218 9.3.5 Ensemble Models 219 9.3.6 Transformer-based Models 220 9.3.7 Large Language Models 223 9.4 Dataset 224 9.5 Evaluation 236 9.5.1 Price Prediction Models 236 9.5.1.1 Regression and Classification Models 236 9.5.1.2 Deep Learning Models 237 9.5.2 Sentiment Analysis Models 242 9.5.2.1 Traditional ML Approaches 242 9.5.2.2 DL Models 245 9.5.3. Hybrid Models 247 9.5.4 Market Dynamics and External factors 251 9.6 Limitations 253 ftoc.indd 17 6/19/2025 2:48:49 PM xviii Table of Contents 9.7 Future Recommendations 254 9.7.1 Advanced Modeling Techniques and Performance Enhancement 255 9.7.2 Sentiment Analysis and Social Media Integration 256 9.7.3 Market Dynamics and Behavioral Analysis 256 9.8 Conclusion 257 References 258 10 Artificial Intelligence in Aviation 263 Dr. Dimitrios Ziakkas, USA 10.1 Introduction to Artificial Intelligence in Aviation 263 10.1.1 Historical Context and Evolution of AI in Aviation 263 10.1.2 Significance of AI in Aviation 263 10.2 AI in Flight Operations and Training 264 10.2.1 AI in Pilot Training 265 10.2.2 Virtual and Augmented Reality in Pilot Training 265 10.2.3 SiPO and Advanced Air Mobility 266 10.2.4 Predictive Analytics for Aircraft Health Monitoring 266 10.3 AI in Air Traffic Management 267 10.3.1 AI-driven ATC Systems 267 10.3.2 AI in UAS and Drone Management 268 10.3.3 Predictive Analytics in ATM 268 10.4 AI in Airport Operations 268 10.4.1 AI Applications in Airport Security and Surveillance 269 10.4.2 AI-enabled Remote Towers and Ground Operations 269 10.4.3 AI in Predictive Maintenance and Energy Management 269 10.5 AI in Customer Experience and Service 270 10.5.1 AI-driven Virtual Assistants and Chatbots 270 10.5.2 Dynamic Pricing and AI-enhanced Revenue Management 270 10.5.3 AI in Personalized Recommendations and Customer Loyalty Programs 271 10.5.4 AI in Real-time Customer Feedback and Sentiment Analysis 271 10.6 AI in Maintenance and Technical Support 272 10.6.1 Predictive Maintenance and Aircraft Health Monitoring 272 10.6.2 Fault Detection, Diagnosis, and Prognosis 273 10.6.3 AI in Supply Chain and Spare Parts Management 273 10.6.4 AI in Automated Technical Support Systems 274 10.7 Human Factors and AI Integration 274 10.7.1 Human–AI Interaction in Aviation 274 10.7.2 Training and Skill Development for Operators 275 10.8 Ethical and Regulatory Challenges 275 10.9 AI Case Studies and Future Prospects 276 10.9.1 Successful AI Implementation in Aviation 276 10.9.2 Challenges and Lessons Learned from AI Integration 277 10.10 The Future of AI in Aviation 278 References 278 ftoc.indd 18 6/19/2025 2:48:49 PM Table of Contents xix 11 Enhancing Engineering Education: A Multimodal Approach to Personalization and Adaptation Using Artificial Intelligence in Game-based Learning 281 Roger Azevedo, Daryn Dever, and Megan Wiedbusch, USA 11.1 Context: Challenges in Engineering Education 281 11.2 GBLEs for Engineering Education: Are They Effective? 283 11.3 Personalization and Adaptivity in GBLEs 284 11.4 Personalization and Adaptivity in GBLEs for Engineering Education: Are They Effective? 284 11.5 Augmenting Personalization and Adaptivity in GBLEs in Engineering Education with Multimodal Trace Data 286 11.6 AI Techniques for Handling Multimodal Approaches to Individualization and Adaptation 288 11.7 Essential SRL Processes from Multimodal Trace Data with GBLEs in Engineering Education 289 11.7.1 Goal Setting 290 11.7.2 Self-monitoring 291 11.7.3 Strategic Planning 292 11.7.4 Self-reflection 292 11.7.5 Time Management 293 11.7.6 Help-seeking 295 11.7.7 Resource Management 296 11.8 Open Questions, Future Directions, and Conclusions 297 Acknowledgments 299 References 299 12 Securing Artificial Intelligence Systems in the Era of Large Language Models 307 Carmen-Gabriela Stefanita, USA 12.1 The Need for an Artificial Intelligence Risk Management Framework in an Evolving Artificial Intelligence Landscape 307 12.1.1 Threats of Cyberattacks Against AI Require Proactive Measures 307 12.1.2 Security Risks Associated with Private, Public, or Hybrid Cloud Implementation 308 12.1.3 Business, Legal and Cybersecurity Risks 310 12.2 Security for AI Threat Model 313 12.2.1 Conventional Threat Model Foundation 314 12.2.2 Conventional Threat Management 314 12.2.3 Conventional Threats Take on New Meanings 315 12.2.4 New Threat Landscape: Generative AI Specific Risks 316 12.3 Implementing a Security for AI Framework 317 12.3.1 Matrix of Security Controls 318 12.3.2 Enforcement of Security Controls 319 12.3.3 Security Controls Extended to LLMs 320 12.4 Conclusion 323 Acknowledgments 324 Notes 324 ftoc.indd 19 6/19/2025 2:48:49 PM xx Table of Contents 13 Responsible Artificial Intelligence Applications for Social Good 327 Ozlem Garibay and Brent Winslow, USA 13.1 Introduction 327 13.2 Ethical Aspects of AI for Social Good Applications 328 13.2.1 Definitions, Applications, and Mitigation Strategies for Bias and Fairness 328 13.2.2 Definitions, Applications, and Mitigation Strategies for Interpretability and Explainability 330 13.2.3 Definitions, Applications, and Mitigation Strategies for Privacy and Security 331 13.3 AI Applications for Healthcare 331 13.3.1 Remote Health Monitoring and Intervention 332 13.3.2 Drug Discovery and Personalized Medicine 332 13.3.3 Epidemic Prediction and Management 333 13.3.4 AI in Medical Imaging and Diagnostics 334 13.3.5 Ethical Considerations in Healthcare AI 334 13.4 AI for Environmental Sustainability 335 13.4.1 Introduction 335 13.4.2 AI for Climate Change Monitoring and Modeling 336 13.4.3 AI for Sustainable Agriculture and Food Production 336 13.4.4 AI for Wildlife Conservation 337 13.4.5 AI for Renewable Energy Optimization 337 13.4.6 Ethical Considerations in Environmental AI 337 13.5 AI for Education and Accessibility 338 13.5.1 Personalized Learning with AI 338 13.5.2 Ethical Aspects of AIED 339 13.6 AI in Humanitarian Efforts and Disaster Response 340 13.6.1 Early Warning Systems 340 13.6.2 Disaster Response and Relief 340 13.6.3 Humanitarian Crisis Response 341 13.6.4 Ensuring Fairness and Transparency in AI for Humanitarian Efforts 341 13.7 Conclusion 342 References 343 14 Future Directions and Applications of Artificial Intelligence 355 Ivan Garibay, Clayton Barham, Sina Abdidizaji, Chathura Jayalath, USA 14.1 Introduction 355 14.2 Emerging Trends of AI for Industrial Engineering 356 14.2.1 Digital Twins 356 14.2.2 Large Language Models 358 14.2.3 Agentic AI 358 14.2.4 Graph Neural Networks 359 14.2.5 Embedding Models 359 14.3 Recent Applications 360 14.3.1 Discovering Models via Evolutionary Algorithms and ML 360 Table of Contents xxi 14.3.2 Drug Discovery and Drug–Target Interaction Prediction Using Foundational Molecular Models in Bioinformatics 360 14.3.3 Discovering and Modeling Pathways of Information in Social Media 361 14.4 Future Directions: Explainable AI for Industrial Engineering 361 14.4.1 The Current State of Explainable AI 362 14.4.1.1 Formative Evaluation of User Needs and Types of Approaches 362 14.4.1.2 Algorithm-centric XAI Techniques 363 14.4.1.3 Domain Knowledge Integration as an Emerging Paradigm 364 14.5 Case Study 365 References 366 Index 371
WALDEMAR KARWOWSKI is a Pegasus Professor and Chair in the Department of Industrial Engineering and Management Systems at the University of Central Florida. He is an elected member of The Academy of Science, Engineering and Medicine of Florida (ASEMFL). VINCENT DUFFY is a Professor of Industrial Engineering and Agricultural & Biological Engineering at Purdue University and a Fulbright Senior Scholar. GAVRIEL SALVENDY is a University Distinguished Professor at the University of Central Florida, a member of the National Academy of Engineering, and founding Department Head of Industrial Engineering at Tsinghua University in China.