...covers a broad spectrum of important issues and concepts and should stimulate discussion among clinical epidemiologists and basic scientists interested in the pathophysiology of epilepsy...a lucid, well thought out review of many of the major issues in epilepsy research and much of the progress that has been made over the past few decades. I highly recommend this volume. J.H. Schneiderman, The Canadian Journal of Neurological Sciences ...well written and edited...would provide a more advanced reader an excellent overview of where research on basic mechanisms of the epilepsies now stands, and where it is heading. Robert S. Fisher, Electroencephalography & Clinical Neurophysiology ...this is a book oriented to neuroscientists, neurologists, and neurosurgeons interested in epilepsy, that can clarify many concepts. These concepts are useful tools to understand antiepileptic drug mechanisms, the different age-related sensitivity of the brain to different insults, and the physiological mechanisms of normal brain that support an epileptic activity. Xabier Beristain, Neurological Research This book is an excellent reference for recent work in epilepsy research, in both thought-provoking and technical ways. It is highly recommended for scientists and clinicians interested in epilepsy. Cynthia L. Harden, Quarterly Review of Biology