The emergence of ketamine--previously known as a combat anesthetic and club drug--as a treatment for depression.
The emergence of ketamine--previously known as a combat anesthetic and club drug--as a treatment for depression.
Ketamine, approved in 2019 by the Food and Drug Administration for the treatment of depression, has been touted by scientists and media reports as something approaching a miracle cure. This volume in the MIT Press Essential Knowledge series chronicles the ascent of a drug that has been around for fifty years--in previous incarnations, a Vietnam-era combat anesthetic and a popular club drug--that has now been reinvented as a treatment for depression. Bita Moghaddam, a leading researcher in neuropharmacology, explains the scientific history and the biology of ketamine, its clinical use, and its recently discovered antidepressant effects, for the nonspecialist reader.
By:
Bita Moghaddam Imprint: MIT Press Country of Publication: United States Dimensions:
Height: 178mm,
Width: 127mm,
Weight: 368g ISBN:9780262542241 ISBN 10: 0262542242 Series:MIT Press Essential Knowledge Pages: 136 Publication Date:04 May 2021 Audience:
General/trade
,
ELT Advanced
Format:Paperback Publisher's Status: Active
Series Foreword ix Preface xi 1 The Molecule Ketamine 1 2 Uses of Ketamine 17 3 Neuroscience of Ketamine 31 4 Ketamine as an Antidepressant 65 5 How Does Ketamine Produce Antidepressant Effects? 101 6 Safety Concerns with Ketamine and Esketamine 121 7 Where Do We Go from Here? 141 Acknowledgments 155 Glossary 157 Notes 161 Further Reading 177 Index 179
Bita Moghaddam is a leading researcher in the field of neuropsychopharmacology. She is Ruth Matarazzo Professor of Behavioral Neuroscience at Oregon Health and Science University in Portland.