Quantitative Fundamentals of Molecular and Cellular Bioengineering

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K. Dane Wittrup (C. P. Dubbs Professor of Chemical Engineering and Bioengineering, Massachusetts Institute of Technology) Bruce Tidor (Professor of Biological Engineering and Computer Science, Massachusetts Institute of Technology)

Quantitative Fundamentals of Molecular and Cellular Bioengineering

K. Dane Wittrup (C. P. Dubbs Professor of Chemical Engineering and Bioengineering, Massachusetts Institute of Technology), Bruce Tidor (Professor of Biological Engineering and Computer Science, Massachusetts Institute of Technology), Benjamin J. Hackel (Associate Professor, University of Minnesota) , Casim A. Sarkar (Associate Professor, University of Minnesota)

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MIT Press
07 January 2020

Molecular biology; Pharmaceutical technology

Series: The MIT Press

A comprehensive presentation of essential topics for biological engineers, focusing on the development and application of dynamic models of biomolecular and cellular phenomena.

This book describes the fundamental molecular and cellular events responsible for biological function, develops models to study biomolecular and cellular phenomena, and shows, with examples, how models are applied in the design and interpretation of experiments on biological systems. Integrating molecular cell biology with quantitative engineering analysis and design, it is the first textbook to offer a comprehensive presentation of these essential topics for chemical and biological engineering.

The book systematically develops the concepts necessary to understand and study complex biological phenomena, moving from the simplest elements at the smallest scale and progressively adding complexity at the cellular organizational level, focusing on experimental testing of mechanistic hypotheses. After introducing the motivations for formulation of mathematical rate process models in biology, the text goes on to cover such topics as noncovalent binding interactions; quantitative descriptions of the transient, steady state, and equilibrium interactions of proteins and their ligands; enzyme kinetics; gene expression and protein trafficking; network dynamics; quantitative descriptions of growth dynamics; coupled transport and reaction; and discrete stochastic processes. The textbook is intended for advanced undergraduate and graduate courses in chemical engineering and bioengineering, and has been developed by the authors for classes they teach at MIT and the University of Minnesota.

By: K. Dane Wittrup (C. P. Dubbs Professor of Chemical Engineering and Bioengineering Massachusetts Institute of Technology), Bruce Tidor (Professor of Biological Engineering and Computer Science, Massachusetts Institute of Technology), Benjamin J. Hackel (Associate Professor, University of Minnesota), Casim A. Sarkar (Associate Professor, University of Minnesota)
Imprint: MIT Press
Country of Publication: United States
Dimensions: Height: 229mm, Width: 178mm, Spine: 32mm
ISBN: 9780262042659
ISBN 10: 0262042657
Series: The MIT Press
Pages: 592
Publication Date: 07 January 2020
Recommended Age: From 18 to 99 years
Audience: College/higher education , Primary
Format: Hardback
Publisher's Status: Active

K. Dane Wittrup is C. P. Dubbs Professor of Chemical Engineering and Biological Engineering at MIT and the Koch Institute for Integrative Cancer Research at MIT. Bruce Tidor is Professor of Biological Engineering and Computer Science at MIT. Benjamin J. Hackel is Associate Professor of Chemical Engineering and Materials Science at the University of Minnesota. Casim A. Sarkar is Associate Professor of Biomedical Engineering at the University of Minnesota.

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Quantitative Fundamentals of Molecular and Cellular Bioengineering

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