Immunosenescence

Andreas Thiel

$384.95 $307.85

Hardback

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English

Birkhauser Verlag AG
16 February 2012

Medical research; Maturation & ageing; Immunology

Series: Birkhäuser Advances in Infectious Diseases

As individuals age, their ability to respond to and clear pathogens and to control unwanted immune reactions declines, leading to a greater incidence of certain infectious diseases, autoimmunity and general immune dysfunctions. Most remarkably, the efficacy of vaccines is frequently decreased in elderly persons. Therefore, age-associated dysfunctions of the humoral and cellular immune responses have a strong clinical impact. Improving our understanding of the aged immune system is crucial in developing effective prevention and treatment programs that will facilitate healthy aging and improve the quality of life of the elderly population.

The aim of this volume is to summarize current knowledge on the cellular and molecular aspects of the aging immune system, with an emphasis on infectious diseases and new therapeutic approaches.

Edited by: Andreas Thiel
Imprint: Birkhauser Verlag AG
Country of Publication: Switzerland
Edition: 2012 ed.
Dimensions: Height: 235mm, Width: 155mm, Spine: 23mm
Weight: 553g
ISBN: 9783034602181
ISBN 10: 3034602189
Series: Birkhäuser Advances in Infectious Diseases
Pages: 238
Publication Date: 16 February 2012
Audience: Professional and scholarly , Undergraduate
Format: Hardback
Publisher's Status: Active

Regulation of Adaptive Immunity in the Elderly.- Does Innate Immunity Get Old?.- Thy(-Im)Munosenescence: The Ageing of the Thymus and Its Impact on the Immune System.- Characteristics of B Cells and B Cell Responses in Aged Individuals.- Mechanisms of Immune Protection to Pneumococcal Infection in the Young and the Elderly.- CMV Subversion of the Immune System in Later Life.- Aging and Autoimmunity.- Vaccination in the Elderly.- Immunosenescence and the 3r’s; Restoration, Replacement and Reprogramming.- Novel Strategies of Improved Vaccines for Elderly: The Example of Influenza.

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Immunosenescence

Andreas Thiel

$384.95 $307.85

Hardback

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