Parasitic Infections Understand and defeat a scourge of public health with this cutting-edge guide
Parasitic diseases are considered as an important public health problem due to the high morbidity and mortality rates, particularly in countries where climate and level of economic development create serious challenges to the creation of public health infrastructure, thus can make parasitic infections both graver and more difficult to contain. As we come to understand the global ramifications of public health, there has never been a more crucial time to understand these infections and the processes by which they can be managed and defeated.
Parasitic Infections is a comprehensive overview of parasitic immunopathology, including the fundamentals of parasite biology, mechanisms and processes of infection, and the key steps of drug discovery and treatment. In addition to detailed coverage of the most commonly encountered infectious parasites, analysis of the immune system provides material pertinent to any possible parasitic infection. The result is an essential contribution to public health research.
Parasitic Infections readers will also find:
A careful balance of parasite immunopathology and pharmaceutical analysis Detailed discussion of parasites such as protozoans, helminths, and ectoparasites Case studies and in-depth analyses written by authors around the world on the basis of first hand investigation
Parasitic Infections is a must-read for researchers or professionals in immunology, biology, medicinal chemistry, drug development or pharmaceutical research, and all related fields.
List of Contributors ix Preface xv Acknowledgments xviii 1 Introduction: Back to the Future ‒ Solutions for Parasitic Problems 1 Rahime Şimşek, Aqsa Farooqui, Salah-Ud-Din Khan, and Shahanavaj Khan 2 Induction of Immune Responses and Inflammation to Parasitic Infections 47 Gurdeep Singh, Abhishek Tiwari, Varsha Tiwari, and Mukesh Kr Singh 3 Animal Parasites: Insight into Natural Resistance 60 Nasib Zaman, Muhammad Rizwan, Kishawar Sultana, Abdur Rauf, Yahya S. Al-Awthan, and Omar Bahattab 4 Immune Response against Protozoan Parasites 73 Ahmed Olatunde, Olalekan Ogunro, Habibu Tijjani, Shakir Mayowa Obidola, Mustapha Abdullahi Akpaki, Archana Yadav, Manisha Nigam, and Abhay Prakash Mishra 5 Immune Response against Helminths 100 Varsha Tiwari, Abhishek Tiwari, Gurdeep Singh, and Mukesh Kr Singh 6 Ectoparasites Host Resistance and Tolerance 124 Jacob Kehinde Akintunde and Ayodeji Mathias Adegoke 7 Microorganisms as Drivers of Host‒Parasite Interactions 141 Rahul Negi, Munni Bhandari, Rahul Kunwar Singh, and Tribhuvan Mohan Mohapatra 8 Neglected Parasitic Infections: History to Current Status 156 Sarmistha Debbarma, Jupi Talukdar, Prabhakar Maurya, Luit Moni Barkalita, and Anupam Brahma 9 Molecular Techniques for the Study and Diagnosis of Parasite Infection 176 Syed Muhammad Mukarram Shah, Saira, and Fida Hussain 10 Drugs for the Control of Parasitic Diseases: Current Status and Case Studies 205 Pratichi Singh, Swetanshu, Shikha Yadav, Adeline Lum Nde, and Vijay Jyoti Kumar 11 Opportunities and Challenges in the Development of Antiparasitic Drugs 227 Maryam Bello-Akinosho, Kayode Olayinka Afolabi, Harish Chandra, Dearikha Karina Mayashinta, Yulia Dwi Setia, and Carolina Pohl-Albertyn 12 Phytopharmaceuticals as an Alternative Treatment against Parasites 251 Rajesh Kumar, Seetha Harilal, Arti Gautam, Manisha Nigam, and Abhay Prakash Mishra 13 Nanoparticles for Antiparasitic Drug Delivery 303 Abdulkadir Mohammed Danyaro, Habibu Tijjani, Swinder Jeet Singh Kalra, and Ahmed Olatunde 14 Vaccination Against Parasitic Infection: From Past to Current Approaches in the Development of a Vaccine 328 Mukesh Kr Singh, Gurdeep Singh, Varsha Tiwari, and Abhishek Tiwari 15 Current Trends in Parasitic Diseases and Precautionary Measures 356 Nisha Singh Index 382
Abhay Prakash Mishra, PhD, is a Postdoctoral Fellow in the Department of Pharmacology, University of Free State, South Africa. He has extensive research experience in drug development and other research areas related to parasitic infection. Manisha Nigam, PhD, is Assistant Professor and Head of Department of Biochemistry, School of Life Sciences, Hemvati Nandan Bahuguna Garhwal University, India. She has extensive research and teaching experience regarding cancer biology, parasite biology and immunopathology.
