Oxazole, Isoxazole, Benzoxazole-Based Drug Discovery

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Erum Akbar Hussain (Tenured Associate Professor, Lahore College, Women University, Pakistan) Ambreen Ghani (Assistant Professor, Division of Science and Tech, University of Education, Pakistan)

Oxazole, Isoxazole, Benzoxazole-Based Drug Discovery

Erum Akbar Hussain (Tenured Associate Professor, Lahore College, Women University, Pakistan), Ambreen Ghani (Assistant Professor, Division of Science and Tech, University of Education, Pakistan), Zubi Sadiq (Research Associate, Department of Chemistry, Lahore College, Pakistan)

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English

Elsevier - Health Sciences Division
14 June 2024

Pre-clinical medicine: basic sciences; Chemistry; Organic chemistry; Pharmaceutical technology

Series: Heterocyclic Drug Discovery

Oxazole, Isoxazole, Benzoxazole Based Drug Discovery offers complete coverage of oxazole and related molecules, both from natural and synthetic origin, with a focus on the reaction mechanisms, and medicinal, pharmacokinetic and computational aspects. New and contemporary methods of synthesis are discussed, with a special focus on green, environment-friendly procedures. Discussion of stereochemical studies, particularly on natural molecules, are included. Computational chemistry has emerged as an integral tool for drug discovery, hence this book explains how the drug candidate is established as suitable for clinical trials with the help of molecular docking and virtual screening modeling.

This book offers a broad range of recent developments and detailed coverage of synthesis and biological activities of the drugs, and is an ideal reference guide to researchers working in organic and medicinal chemistry.

By: Erum Akbar Hussain (Tenured Associate Professor Lahore College Women University Pakistan), Ambreen Ghani (Assistant Professor, Division of Science and Tech, University of Education, Pakistan), Zubi Sadiq (Research Associate, Department of Chemistry, Lahore College, Pakistan)
Imprint: Elsevier - Health Sciences Division
Country of Publication: United States
Dimensions: Height: 229mm, Width: 151mm,
ISBN: 9780323853866
ISBN 10: 0323853862
Series: Heterocyclic Drug Discovery
Pages: 420
Publication Date: 14 June 2024
Audience: Professional and scholarly , Undergraduate
Format: Paperback
Publisher's Status: Forthcoming

1. Introduction 2. Oxazoles 3. Isoxazoles 4. Bioactive Benzoxazole 5. Oxadiazole 6. Oxazolidine 7. Oxazolidinone 8. Oxazoline 9. Oxazolone 10. Conclusion

Erum Akbar Hussain studied Chemistry and received her PhD in 2002 from ICCB, H.E.J Research Institute of Chemistry, University of Karachi, Pakistan. At present, she is Tenured Associate Professor at Lahore College for Women University. Her research is focused on understanding hetero annulation reactions under the umbrella of green chemistry. Ambreen Ghani is working as Assistant Professor at University of Education, Division of Science and Technology, Lahore, Vehari Campus. She has earned PhD in 2018 from Lahore College for Women University Lahore. Her research interests include the design and synthesis of selective anti-inflammatory agents. Zubi Sadiq is currently working as a Research Associate at Lahore College for Women University, Lahore, Pakistan. She received her Ph.D. in Chemistry (2019) from same University. She received a gold medal and academic roll of honour in her MS degree. She was a lecturer of Chemistry (2012 - 2013) at Preparatory Year Deanship, King Faisal University, Al-Ahsa, Saudi Arabia. Her research interests encompass various areas of synthesis and sustainable Chemistry.