THE BIG SALE IS ON! TELL ME MORE

Close Notification

Your cart does not contain any items

KCNQ2- and KCNQ3-Associated Epilepsy

Sarah Weckhuysen Alfred L. George, Jr

$32.95

Paperback

Not in-store but you can order this
How long will it take?

QTY:

English
Cambridge University Press
01 December 2022
KCNQ2 and KCNQ3 encode subunits (KV7.2, KV7.3) that combine to form a voltage-gated potassium ion (K+) channel responsible for generating an ionic current (M-current) important for controlling activity in the nervous system. Pathogenic variants in both genes are associated with a spectrum of genetic neurological disorders that feature epilepsy of variable severity and can be accompanied by debilitating impaired neurodevelopment. These two genes were among the first discovered causes of monogenic epilepsy, and are frequently identified in persons with early-life epilepsy. This Element provides a comprehensive review of the clinical features, genetic basis, pathophysiology, pharmacology and treatment of these prototypical neurological disorders accompanied by perspectives shared by affected families and scientists who have made seminal contributions to the field. This title is also available as Open Access on Cambridge Core.

Edited by:   , ,
Imprint:   Cambridge University Press
Country of Publication:   United Kingdom
Dimensions:   Height: 228mm,  Width: 152mm,  Spine: 7mm
Weight:   180g
ISBN:   9781009278263
ISBN 10:   1009278266
Series:   Elements in Genetics in Epilepsy
Pages:   75
Publication Date:  
Audience:   General/trade ,  ELT Advanced
Format:   Paperback
Publisher's Status:   Active

See Also