Applications in Forensic Proteomics: Protein Identification and Profiling

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Eric D. Merkley (Scientist, Scientist, Pacific Northwest National Laboratory) Eric D Merkley

Applications in Forensic Proteomics

Protein Identification and Profiling

Eric D. Merkley (Scientist, Scientist, Pacific Northwest National Laboratory), Eric D Merkley

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English

Oxford University Press Inc
10 December 2020

Forensic science; Criminology: legal aspects

Series: ACS Symposium Series

"Proteomics is a mature research tool in the life sciences, and it can be a powerful addition to the forensic science toolbox. This work presents several areas in which proteomics was used to answer forensic questions. Illustrating current applications of proteomic methods, this work introduces opportunities for proteomics to answer compelling questions in forensic science and biosecurity. These ""case studies"" will be valuable to both practicing forensic scientists and researchers developing proteomics methods."

Edited by: Eric D. Merkley (Scientist Scientist Pacific Northwest National Laboratory)
Other: Eric D Merkley
Imprint: Oxford University Press Inc
Country of Publication: United States
Dimensions: Height: 260mm, Width: 184mm, Spine: 22mm
Weight: 778g
ISBN: 9780841236493
ISBN 10: 0841236496
Series: ACS Symposium Series
Pages: 248
Publication Date: 10 December 2020
Audience: Professional and scholarly , Undergraduate
Format: Hardback
Publisher's Status: No Longer Our Product

Chapter 1. Introduction to Forensic Proteomics, Eric D. Merkley Chapter 2. A Proteomics Tutorial, Eric D. Merkley, Brooke L. D. Kaiser, and Helen Kreuzer Chapter 3. Proteomic Sample Preparation Techniques: Toward Forensic Proteomic Applications, Carrie Nicora, Marina Gritsenko, Anna Lipton, Karen L. Wahl, and Kristin E. Burnum-Johnson Chapter 4. NextGen Serology: Leveraging Mass Spectrometry for Protein-Based Human Body Fluid Identification, Heather E. McKiernan, Catherine O. Brown, Luciano Chaves Arantes, Phillip B. Danielson, and Kevin M. Legg Chapter 5. Informatics Approaches to Forensic Body Fluid Identification by Proteomic Mass Spectrometry, Wenke Liu, Erin Butler, Heyi Yang, David Fenyo, and Donald Siegel Chapter 6. Fingermarks as a New Proteomic Specimen: State of the Art and Perspective of In Situ Proteomics, Simona Francese and Cristina Russo Chapter 7. Human Identification Using Genetically Variant Peptides in Biological Forensic Evidence, Fanny Chu, Katelyn E. Mason, Deon S. Anex, Phillip H. Paul, and Bradley R. Hart Chapter 8. Proteomics in the Analysis of Forensic, Archaeological, and Paleontological Bone, Michael Buckley Chapter 9. Proteomics for Microbial Forensics, Eric D. Merkley Chapter 10. ISO 17025 Accreditation of Method-Based Mass Spectrometry for Bioforensic Analyses, Stephen R. Cendrowski and Alaine M. Garrett Chapter 11. Unambiguous Identification of Ricin and Abrin with Advanced Mass Spectrometric, Assays Suzanne R. Kalb and Francois Becher Chapter 12. Challenges in the Development of Reference Materials for Protein Toxins, R. Zeleny, A. Rummel, D. Jansson, and B. G. Dorner Chapter 13. The Statistical Defensibility of Forensic Proteomics, Kristin H. Jarman and Eric D. Merkley Editors' Biographies Author Index Subject Index

Eric D. Merkley earned a B.S. in biochemistry from Brigham Young University in 2003 and Ph.D. in biochemistry from the University of Washington in 2010. He completed post-doctoral studies in the well-known proteomics research group at Pacific Northwest National Laboratory (PNNL). In 2013, Dr. Merkley joined PNNL's Chemical and Biological Signature Sciences Group. Research interests include mass spectrometric analysis of biothreat agents and protein toxins, strengthening proteomics bioinformatics strategies to ensure readiness for forensic and legal applications, and developing standards for forensic applications of proteomics.