Tuberculosis

The Microbe Host Interface

Larry S. Schlesinger, Lucy DesJardin

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Hardback

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English

Taylor & Francis
09 October 2003

Infectious & contagious diseases

M. tuberculosis remains one of the most successful human pathogens known. The causative agent of tuberculosis, it also has an unique ability to persist for years in the infected, apparently healthy host. This dormant organism can be reactivated years, even decades later to cause tuberculosis. Knowledge regarding the interaction of M. tuberculosis with the host is fundamental to understanding the pathogenesis; leading eventually to the development of strategies for the prevention and control of infection and disease. By integrating genetic, microbiologic, immunologic, and cell biologic approaches to elucidate pathogenesis, penetrating new insights into the interaction of M. tuberculosis with the host have emerged. This book reviews the most important state-of-the-art approaches currently used to study microbe-host interactions and highlights emerging methodologies. Strategies to analyze the following topics are included: mycobacterial entry, growth, and gene expression in macrophages; analysis of post-phagocytic events; analysis of signaling in infected macrophage; the acquired immune response; newer animal- and non animal-models systems; latency; and the epidemiology of M. tuberculosis infections.

By: Larry S. Schlesinger, Lucy DesJardin
Imprint: Taylor & Francis
Edition: New edition
Dimensions: Height: 229mm, Width: 152mm, Spine: 234mm
Weight: 680g
ISBN: 9780954523213
ISBN 10: 0954523210
Pages: 292
Publication Date: 09 October 2003
Audience: College/higher education , Professional and scholarly , Primary , Undergraduate
Format: Hardback
Publisher's Status: Active

Larry S. Schlesinger (The Ohio State University, USA) (Author), Lucy DesJardin (University of Iowa, USA) (Author)

Reviews for Tuberculosis: The Microbe Host Interface

This book presents state-of-the art knowledge of the interface of M tuberculosis with the host to understand the nature of the host response to this infectious process. Microbiologists, molecular biologists, clinicians, and pharmaceutical and biotechnology scientists will find this source of current knowledge on tuberculosis pathogenesis upgrading and inspiring.. #46 (5)-Veterinary and Human Toxicology, October 2004 The contents of this book are most timely considering the worldwide reappearance of TB.... Vol. 8, No. 3-E-Streams, March 2005 ... This book is an excellent interdisciplinary exposure to host - M.tuberculosis interaction in the widest sense. ...It will provide a superb foundation for the almost inevitable further study needed to stay abreast of this rapidly changing area. . 2004:40; Book Reviews-CID [Clinical Infectious Diseases], 02/15/2005