First published in 1986: This two-volume set provides essential information on the general princi-ples of target organ toxicity. Pharmacokinetics, metabolic activation and key defense mechanisms, excretion, species variation, and tissue-specific biochemistry are explored comprehensively. These general principles are then illustrated using specific examples of toxicity to different target organs and systems. DNA modifi-cation and repair in tumor induction, and specificity in tumor initiation are also examined. Of primary interest to toxicologist, pharma-cologists, biochemists, and environmental toxicologists.
Edited by:
Gerald M. Cohen Imprint: CRC Press Country of Publication: United Kingdom Dimensions:
Height: 280mm,
Width: 210mm,
Weight: 453g ISBN:9780367258719 ISBN 10: 0367258714 Series:Routledge Revivals Pages: 234 Publication Date:30 June 2020 Audience:
Professional and scholarly
,
Undergraduate
Format:Hardback Publisher's Status: Active
Gerald M. Cohen Ph.D. is Head of the Toxicology Unit, Department of Pharmacology, The School of Pharmacy, University of London.