Synthetic Nucleic Acids as Inhibitors of Gene Expression: Mechanisms, Applications, and Therapeutic Implications...

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Levon Michael Khachigian (University of New South Wales, Australia) Levon Michael Khachigian (University of New South Wales, Australia)

Synthetic Nucleic Acids as Inhibitors of Gene Expression

Mechanisms, Applications, and Therapeutic Implications

Levon Michael Khachigian (University of New South Wales, Australia), Levon Michael Khachigian (University of New South Wales, Australia), Ryuichi Morishita , Noboru Fukuda

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English

CRC Press Inc
29 November 2004

Genetics (non-medical); DNA & Genome

In the post-genomic era we have, at our fingertips, complete genome sequences and huge numbers of predicted

gene sequences from a multitude of complex organisms. There

remains, however, the critical need to understand the functions of these gene products to delineate the precise roles of these genes in complex biological milieu. Synthetic nucleic acids are at the cutting-edge of molecular strategies that

target genes of interest in a specific and cost-effective manner. These agents are now being used as new and exciting gene-silencing agents in vitro, in animal models of disease, and in humans. This book brings together timely authoritative, in-depth reviews by renowned international leaders in the

fields of ribozymes, RNA interference, DNAzymes and oligonucleotide decoys, with emphasis on biochemistry and translational research.

Contributions by: Ryuichi Morishita, Noboru Fukuda, Mehdi Nosrati
Edited by: Levon Michael Khachigian (University of New South Wales Australia), Levon Michael Khachigian (University of New South Wales, Australia)
Imprint: CRC Press Inc
Country of Publication: United States
Dimensions: Height: 234mm, Width: 156mm, Spine: 17mm
Weight: 408g
ISBN: 9780849330254
ISBN 10: 0849330254
Pages: 204
Publication Date: 29 November 2004
Audience: Professional and scholarly , Undergraduate
Format: Hardback
Publisher's Status: Active

Levon Michael Khachigian