Liu, Kai
The Collegium Internationale Allergologicum (CIA) is a group of leading scientists and doctors from all over the world who meet every two years to present and discuss, in an outstanding symposium, their most recent unpublished research. The CIA is a numerus clauses organization with very selective criteria of admission. Only one contribution from each research group can be presented at CIA Symposia by group leaders or upon invitation. If you are not a member of the CIA but you wish to be part of this sophisticated club, the book From Genes to Phenotypes will allow you to be aware of data presented at the last CIA meeting held in Bornholm. Most symposia proceedings are quite heterogeneous in their contents. On the contrary, the book of H. Lowenstein, J. Bienenstock and J. Ring answers the need of including the 70 contributions into ten homogeneous sections which go from Basic Mechanisms of Allergy, Allergens, Allergy Regulatory and Effector Cells (dendritic cells and mast cells), News to Clinical Aspects such as Asthma, Food Allergy, Diagnostic and Therapy. The book is also immune from another defect of symposia proceedings, i.e. to be old at the time of publication. In fact, since all contributions presented at CIA meetings represent the most recent unpublished research from top centers, the volume published by Hogrefe & Huber becomes an update Year Review of the most recent and exciting allergy papers. In the road from genes to phenotypes the publication covers topics such as gene-environment interactions, T cell regulation, new molecules and receptors, signal transduction mechanisms of inflammatory cells, new therapeutic approaches to allergic diseases (anti IL-5, DNA vaccination, anti-IgE therapy, molecules which induce tolerance or immune deviation). Since each contribution is quite short (3-4 pages), the main message of it is emphasised and easily captured by readers. by Prof. Sergio Bonini