Research and Applications in Bacteriocins

Margaret A. Riley, Osnat Gillor

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Hardback

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English

Horizon
02 November 2006

Genetics (non-medical); Bacteriology (non-medical)

Bacteriocins comprise a large and functionally diverse family of toxins found in most microbial species. They play a critical role in mediating microbial interactions and in maintaining microbial diversity. The dramatic rise in antibiotic-resistant bacteria has resulted in renewed efforts to find new antimicrobials. Bacteriocins are an attractive focus for drug development because bacteriocins are active against most pathogens, already exist in nature, are remarkably stable, and are not toxic to human cells. Recently, significant advances have enhanced our understanding of the genetics of bacteriocin production and of their mode of action. Research is currently under way to improve the efficacy of bacteriocins by genetic manipulation and to enable their production in non-native hosts.

The authors in this book discuss the identification and characterisation of this diverse group of protein toxins and review the ever-increasing number of potential applications in human health, veterinary medicine, crop management, agriculture, food preservation and bioremediation. Topics covered include biosynthesis, structure and function, genetic modification, cytotoxic activity, potential as antimicrobials, and applications in agriculture and veterinary health.

Edited by: Margaret A. Riley, Osnat Gillor
Imprint: Horizon
Country of Publication: United Kingdom
Dimensions: Height: 234mm, Width: 156mm, Spine: 19mm
Weight: 566g
ISBN: 9781904933236
ISBN 10: 1904933238
Pages: 226
Publication Date: 02 November 2006
Audience: College/higher education , Professional and scholarly , Professional & Vocational , A / AS level , Further / Higher Education
Format: Hardback
Publisher's Status: Active

Margaret A. Riley