Editor-in-Chief: Nicholas J. Talley, MD, PhD, Chair, Department of Internal Medicine, Mayo Clinic College of Medicine, Jacksonville, Florida, USA Associate editors: Keith D. Lindor, MD, Professor of Medicine, Division of Gastroenterology and Hepatology, Mayo Clinic College of Medicine, Rochester, MN, USA Hugo E. Vargas, MD, Chair, Division of Hepatology, Professor of Medicine, Consultant, Divisions of Hepatology and Gastroenterology, Mayo Clinic College of Medicine, Scottsdale, AZ, USA