Mitochondrial Medicine

Salvatore DiMauro, Michio Hirano, Eric A. Schon

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Hardback

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English

CRC Press
19 April 2006

Medicine: general issues; Neurology & clinical neurophysiology; Molecular biology

Mitochondrial dysfunction is increasingly being recognized as the basis of a wide variety of human diseases. Providing an authoritative update on our current knowledge of mitochondrial medicine, this text draws together world authorities from various fields to present general therapeutic strategies, as well as the treatments presently available in different specialties - thus making it essential reading for clinicians involved with the management of patients with mitochondrial diseases. A unique work, this text covers a range of specialties, including cardiology, ophthalmology, otology, nephrology, gastroenterology, hematology-oncology, and reproductive medicine, and does not focus exclusively on the more commonly known neurologic conditions. An accessible, user-friendly text, it also presents translational concepts of mitochondrial biogenesis and genetics in vignettes related to specific questions raised by the disease under discussion, rather than concentrating on basic science, which can often intimidate clinicians. This pioneering work is primarily directed to a clinical audience who are interested in the diverse and diagnostically challenging clinical presentations of mitochondrial diseases and their pathophysiology.

By: Salvatore DiMauro, Michio Hirano, Eric A. Schon
Imprint: CRC Press
Country of Publication: United Kingdom
Dimensions: Height: 246mm, Width: 189mm, Spine: 23mm
Weight: 1.156kg
ISBN: 9781842142882
ISBN 10: 1842142887
Pages: 16
Publication Date: 19 April 2006
Audience: Professional and scholarly , Undergraduate
Format: Hardback
Publisher's Status: Active

Introduction: The Birth of Mitochondrial Medicine. The Mitochondrial Respiratory Chain and its Disorders. Mitochondrial Neurology I. Mitochondrial Neurology II - Myopathies and Peripheral Neuropathies. Mitochondrial Cardiology. Mitochondrial Ophthalmology. Mitochondrial Gastroenterology. Mitochondrial Otology. Mitochondrial Endocrinology. Mitochondrial Nephrology. Mitochondrial Haematology and Oncology. Mitochondrial Reproductive Medicine. Mitochondrial Psychiatry. Mitochondrial Dysfunction and Neurodegenerative Disorders. Therapeutic Approaches Index and Bibliographies

Salvatore DiMauro MD, Lucy G Moses Professor of Neurology Department of Neurology Columbia University Medical Center, New York. Michio Hirano MD, Associate Professor of Neurology Department of Neurology, Columbia University Medical Center New York. Eric A Schon PhD, Lewis P Rowland Professor of Neurology, Department of Neurology, Professor of Genetics and Development (in Neurology) Department of Genetics and Development Columbia University Medical Center New York.

Reviews for Mitochondrial Medicine

<p> Attractive to read not only for paediatricians and neurologists familiar with these devastating disorders but definitely also for a broad range of other, if not all, practicing clinicians and clinical scientists. [...] a wannahave for every medical library! - Jan A.M. Smeitink, Mitochondrion, Feb 2007<p>'This remarkably well-written book is a pleasure to read and to learn from. Mitochondrial Medicine is highly recommended to medical students, residents, practicing neurologists, ophthalmologists, internists, pediatricians, and pathologists.' - Andrew Engel, Annals of Neurology, Vol. 60: 5<p>'This excellent book should become the definitive resource on clinical aspects of mitochondrial diseases ... What this book does superbly is bring together all the clinical aspects into one much-needed resource. The book is edited by experts in the field and is both up-to-date and comprehensive ... Mitochondrial Medicine offers the first comprehensive description of the clinical importance of mi