Lipid Mediators in Allergic Diseases of the Respiratory Tract

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Clive Robinson Peter J. Barnes (Imperial College/National Heart and Lung institute, London, Imperial College School of Medicine, London, UK)

Lipid Mediators in Allergic Diseases of the Respiratory Tract

Clive Robinson, Peter J. Barnes (Imperial College/National Heart and Lung institute, London, Imperial College School of Medicine, London, UK), Richard Beasley , Stephan Townley Holgate (Southampton General Hospital, England, UK)

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English

CRC Press Inc
16 August 1994

Allergies; Respiratory medicine

This volume provides a review of the putative roles of lipid mediators in allergic reactions in the airways. Experts offer comprehensive reviews which focus on key aspects of mediator biology in health and disease, as well as discussing some of the potential problems in assessing the efficacy of novel anti-inflammatory drugs in the lung.

By: Clive Robinson
Contributions by: Peter J. Barnes (Imperial College/National Heart and Lung institute London Imperial College School of Medicine London UK), Richard Beasley, Stephan Townley Holgate (Southampton General Hospital, England, UK), William W. Busse
Imprint: CRC Press Inc
Country of Publication: United States
Dimensions: Height: 254mm, Width: 178mm,
Weight: 748g
ISBN: 9780849354168
ISBN 10: 0849354161
Pages: 268
Publication Date: 16 August 1994
Audience: College/higher education , Professional and scholarly , Professional & Vocational , A / AS level , Further / Higher Education
Format: Hardback
Publisher's Status: Active

The Biosynthesis and Metabolism of Lipid Mediators (C. Robinson). Molecular Mechanisms of Control of Arachidonic Acid Release and Metabolism in Macrophages and Mast Cells (S. Nicosia and O. Letari). Lipoxins: Biosynthesis and Evidence for Their Involvement in Respiratory Diseases (C.N. Serhan). Asthma: Current Mechanistic Concepts (D. Cypcar, N.N. Jarjour, W.W. Busse). Lipid Mediators and Allergic Rhinitis (P.H. Howarth). Eicosanoids in Asthma (J.P. Arm and T.H. Lee). PAF in Respiratory Disease (P.J. Barnes). Quantification of Eicosanoids in the Respiratory Tract (G.W. Taylor). Cytokine Regulation of Eicosanoid Synthesis (W.F. Owen, Jr.). Lipoxygenase Inhibitors and Leukotriene Antagonists as Therapies for Asthma (B.S. Friedman and D.J. Margolskee). A Critique of Single Mediator-Based Interventions: Alternative Approaches to Future Therapy (R. Beasley, H.K. Makker, S.T. Holgate). Future Directions in the Development of Asthma Therapy: Some Reflections on the Lessons Learned with Lipid Mediators (C. Robinson, G. Rosato, and J.F. Parnell). A Strategy for the Discovery of Novel Anti-Asthma Drugs (J. Morley).

Clive Robinson