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Fundamental QSARs for Metal Ions

John D. Walker Michael C. Newman Monica Enache

$126

Paperback

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English
CRC Press
23 September 2019
Fundamental QSARs for Metal Ions describes the basic and essential applications of quantitative structure–activity relationships (QSARs) for regulatory or industrial scientists who need to predict metal ion bioactivity. It includes 194 QSARs that have been used to predict metal ion toxicity and 86 QSARs that have been used to predict metal ion bioconcentration, biosorption, and binding. It is an excellent sourcebook for academic, industrial, and government scientists and policy makers, and provides a wealth of information on the biological and chemical activities of metal ions as they impact health and the environment. Fundamental QSARs for Metal Ions was designed for regulatory and regulated organizations that need to use QSARs to predict metal ion bioactivity, as they now do for organic chemicals. It has the potential to eliminate resources to test the toxicity of metal ions or to promulgate regulations that require toxicity testing of metal ions because the book illustrates how to construct QSARs to predict metal ion toxicity. In addition, the book:

Provides a historical perspective and introduction to developing QSARs for metal ions

Explains the electronic structures and atomic parameters of metals essential to understanding differences in chemical properties that influence cation toxicity, bioconcentration, biosorption, and binding

Describes the chemical properties of metals that are used to develop QSARs for metal ions

Illustrates the descriptors needed to develop metal ion-ligand binding QSARs

Discusses 280 QSARs for metal ions

Explains the differences between QSARs for metal ions and Biotic Ligand Models

Lists the regulatory limits of metals and provides examples of regulatory applications

Illustrates how to construct QSARs for metal ions

Dr. John D. Walker is the winner of the 2013 SETAC Government Service Award.

By:   , ,
Imprint:   CRC Press
Country of Publication:   United Kingdom
Dimensions:   Height: 234mm,  Width: 156mm, 
Weight:   453g
ISBN:   9780367380526
ISBN 10:   0367380528
Pages:   302
Publication Date:  
Audience:   College/higher education ,  Professional and scholarly ,  Primary ,  Undergraduate
Format:   Paperback
Publisher's Status:   Active

Monica Enache hasthirteen years of professional academic experience in Biology. Since 1999 she has been working at the Faculty of Biotechnology of the University of Agricultural Sciences and Veterinary Medicine of Bucharest, Romania. Prior to joining the faculty she has carried out her PhD degree in Liverpool John Moores University (UK), and received her Bachelor of Science degree from the Faculty of Biology of the University of Bucharest (Romania). She is currently a member of the National Society of Cell Biology in Romania, and has authored or co-authoredthen publications andfourteen abstracts for presentations at national or international scientific meetings.

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