Epilepsy: The Intersection of Neurosciences, Biology, Mathematics, Engineering, and Physics

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Ivan Osorio (University of Kansas Medical Center, Kansas City, KS, USA) Hitten P. Zaveri (Yale University, New Haven, CT, USA)

Epilepsy

The Intersection of Neurosciences, Biology, Mathematics, Engineering, and Physics

Ivan Osorio (University of Kansas Medical Center, Kansas City, KS, USA), Hitten P. Zaveri (Yale University, New Haven, CT, USA), Mark G. Frei (Flint Hills Scientific, LLC, Lawrence, KS, USA) , Susan Arthurs (Alliance for Epilepsy Research, Dexter, Michigan, USA)

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English

CRC Press
29 March 2017

Medicine: general issues; Neurology & clinical neurophysiology; Biomedical engineering; Neurosciences; Environmental science, engineering & technology

Epilepsy, one of the most prevalent neurological disorders, affects approximately 1% (greater than 60 million) of the world's population. In an estimated 20 million of these patients, seizures are not controlled even by multiple anti-seizure drugs, and are extremely difficult to predict. Epilepsy: The Intersection of Neurosciences, Biology, Mathematics, Engineering, and Physics seamlessly brings together the neurosciences, mathematics, computational sciences, engineering, physics, and clinical epileptology to present to readers a highly didactic, integrated, clear and practically useful knowledge base and research directions.

Laying out the foundations of signal analysis, data conditioning, linear and non-linear analysis, introduction to dynamical systems and fundamental anatomical and neurophysiological concepts, this book:

Introduces non-physicians to language and concepts necessary to establish a meaningful dialog with epileptologists Introduces physicians to dynamical theory and signal processing without which interdisciplinary collaborations would not be productive

Mines knowledge from fields devoted to the investigation of aperiodic paroxysmal relaxation phenomena, such as earthquakes, which bear dynamical similarities with epilepsy, so as to lay the proper scientific foundations for epileptology and foster much needed therapeutic advances efficiently Reviews spatiotemporal behavior of seizures, mechanisms of epileptogenesis and ictogenesis as well as of seizure control and ancillary technology

Calls attention to nocturnal frontal lobe epilepsy as a potentially fruitful paradigm for advancing seizure prediction.

Of all neurological disorders, epilepsy demands of investigators the broadest and deepest knowledge of dynamical, control, and system theories, knowledge that cannot be amassed without possessing a certain level of sophistication in relevant areas of neurosciences, physics, mathematics, and engineering. Narrowing the inescapable cultural chasm that commonly fragments multidisciplinary efforts, this book captures and enriches the burgeoning interdisciplinary synergism in the nascent field of dynamical epileptology.

Edited by: Ivan Osorio (University of Kansas Medical Center Kansas City KS USA), Hitten P. Zaveri (Yale University, New Haven, CT, USA), Mark G. Frei (Flint Hills Scientific, LLC, Lawrence, KS, USA), Susan Arthurs (Alliance for Epilepsy Research, Dexter, Michigan, USA)
Imprint: CRC Press
Country of Publication: United Kingdom
Dimensions: Height: 254mm, Width: 178mm,
Weight: 453g
ISBN: 9781138074163
ISBN 10: 1138074160
Pages: 578
Publication Date: 29 March 2017
Audience: College/higher education , Professional and scholarly , Primary , Undergraduate
Format: Paperback
Publisher's Status: Active

Foundations of Epilepsy. Foundations of Engineering, Math, and Physics. The Challenge of Prediction. The State of Seizure Prediction: Seizure Prediction and Detection. The State of Seizure Prediction: Seizure Generation. The State of Seizure Prediction: Seizure Control. The State of Seizure Prediction: Technology. Nocturnal Frontal Lobe Epilepsy: A Paradigm for Seizure Prediction?

Hitten P. Zaveri is an Associate Research Scientist within the Department of Neurology at Yale University in New Haven, Connecticut.