Drug Metabolism

Chemical and Enzymatic Aspects

Jack P. Uetrecht, William Trager

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Paperback

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English

CRC Press
18 December 2020

Biology, life sciences

In order to understand drug metabolism at its most fundamental level, pharmaceutical scientists must be able to analyze drug compound structure and predict possible metabolic pathways in order to avoid the risk of adverse reactions that lead to the withdrawal of a drug from the market.

This title is a comprehensive guide for recognizing the chemical underpinnings of drug metabolism.

While there are numerous resources available to medicinal chemists for understanding drug structure, and to pharmacologists for discerning drug metabolism from a biological standpoint, no resource currently exists that links the chemical and biological aspects in language accessible to both-making it challenging for both groups to fully comprehend how a drug is metabolized, as well as the potential effects of the metabolites.

Drug Metabolism: Chemical and Enzymatic Aspects provides extensive material to help understand drug metabolism within a biological context, and for predicting and mitigating adverse drug reactions.

By: Jack P. Uetrecht, William Trager
Imprint: CRC Press
Country of Publication: United Kingdom
Dimensions: Height: 254mm, Width: 178mm,
Weight: 453g
ISBN: 9780367453022
ISBN 10: 0367453029
Pages: 179
Publication Date: 18 December 2020
Audience: Professional and scholarly , Undergraduate
Format: Paperback
Publisher's Status: Active

Background for Non-Chemists. Background for Chemists. Oxidation Pathways and the Enzymes That Mediate Them. Reductive Pathways. Hydolytic Pathways. Conjugation Pathways. Reactive Metabolites

Uetrecht, Jack P. | Trager, William