Cyclic-Nucleotide Phosphodiesterases in the Central Nervous System: From Biology to Drug Discovery

— —

Nicholas J. Brandon Anthony R. West (Rosalind Franklin University of Medicine and Science)

Cyclic-Nucleotide Phosphodiesterases in the Central Nervous System

From Biology to Drug Discovery

Nicholas J. Brandon, Anthony R. West (Rosalind Franklin University of Medicine and Science)

$240.95

Hardback

Not in-store but you can order this
How long will it take?

Availability Information

We source books from suppliers in Australia and overseas. For books we don't currently have in stock, the time it takes to get them from our suppliers can vary widely - from a few days to a few months - so we check each book with each supplier to determine the expected time it will take to be supplied to us.

We then advise you accordingly. If the time taken to get any book is too long for you, you can let us know and we will cancel or adjust your order, and refund as required.

To find out the anticipated arrival time for specific items prior to ordering, please contact us by phone or email:

Phone +61 2 9264 3111, or 1800 4 BOOKS (1800 4 26657) if outside Sydney:
option 1 Abbey's Bookshop (Crime, History, Science, Kids & more) • info@abbeys.com.au
option 2 Language Book Centre (ESL & Foreign Languages) • language@abbeys.com.au
option 3 Galaxy Bookshop (Sci-fi, Fantasy, Romance, Graphic Novels) • sf@galaxybooks.com.au

QTY:

English

John Wiley & Sons Inc
18 April 2014

Medical research; Physiology; Chemistry; Enzymology

Series: Wiley Series in Drug Discovery and Development

This book reviews advances in understanding phosphodiesterases within the central nervous system and their therapeutic applications. A range of expert authors from both academia and industry describe these, then focus on the areas of greatest scientific and medical interest to provide more detailed coverage. Therapeutic and drug discovery applications are covered for diseases including Alzheimer's, Parkinson's, schizophrenia, erectile dysfunction, and spinal cord injuries. There is also a chapter on drug discovery tools such as in vitro assays and X-ray structures for medicinal chemistry studies.

Edited by: Nicholas J. Brandon, Anthony R. West (Rosalind Franklin University of Medicine and Science)
Imprint: John Wiley & Sons Inc
Country of Publication: United States
Dimensions: Height: 241mm, Width: 163mm, Spine: 26mm
Weight: 726g
ISBN: 9780470566688
ISBN 10: 047056668X
Series: Wiley Series in Drug Discovery and Development
Pages: 400
Publication Date: 18 April 2014
Audience: Professional and scholarly , Undergraduate
Format: Hardback
Publisher's Status: Active

NICHOLAS BRANDON works at AstraZeneca within the Neuroscience Innovative Medicines Group. He has spent his career in drug discovery with a strong interest in developing phosphodiesterase inhibitors for neuropsychiatric disorders and understanding the basic mechanisms of phosphodiesterase function. ANTHONY WEST is an Associate Professor in the Department of Neuroscience at Rosalind Franklin University. He has studied PDE function in the basal ganglia for over fifteen years, focusing on neurochemical and electrophysiological changes induced by PDE inhibitors in the healthy brain and in animal models of Parkinson’s disease and Huntington’s disease.