Cryopreservation

Applications in Pharmaceuticals and Biotechnology

Kenneth E. Avis, Carmen M. Wagner

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English

CRC Press
25 September 2019

Biology, life sciences; Pharmaceutical technology

This book covers the principles of cryopreservation as they relate the preservation of viable cells and cell materials being developed for biopharmaceutical applications. Topics include: the principles of freezing and thawing cells, physiochemical phenomena, process and system design options, method selection considerations, preservation procedures, cryoprotectant additives, freeze-drying human live virus vaccines, and transport system selection criteria. Contributions from well-known experts such as Steven S. Lee, Thomas C. Pringle, William H. Siegel, Richard Wisniewski, and Fangdong Yin make this the single most important study available.

Edited by: Kenneth E. Avis, Carmen M. Wagner
Imprint: CRC Press
Country of Publication: United Kingdom
Dimensions: Height: 234mm, Width: 156mm,
Weight: 453g
ISBN: 9780367399399
ISBN 10: 0367399393
Pages: 504
Publication Date: 25 September 2019
Audience: Professional and scholarly , Undergraduate
Format: Paperback
Publisher's Status: Active

Contents include: Principles & Scale-up: Cryopreservation for Cells, Microorganisms, Protein Solutions, Biopharmaceutical Formulations, & Biological Products. Large-Scale Cryopreservation: Process Development for Freezing & Thawing of Large Volumes of Cell Suspensions, Protein Solutions & Biological Products. Methods: Long-Term Preservation of Mammalian Cells & Microorganisms. Cryopreservation of Mammalian Cell Culture Materials. Freeze-Drying of Human Live Virus Vaccines. The Design & Use of Thermal Transport Containers.

Kenneth E. Avis , Carmen M. Wagner