Cap-Analysis Gene Expression (CAGE)

The Science of Decoding Genes Transcription

Piero Carninci

$252

Hardback

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English

Pan Stanford Publishing Pte Ltd
31 October 2009

DNA & Genome

This book is a guide for users of new technologies, as it includes accurately proven protocols, allowing readers to prepare their samples for experiments. Additionally, it is a guide for the bioinformatics tools that are available for the analysis of the obtained tags, including the design of the software, the sources and the Web. Finally, the book provides examples of the application of these technologies to identify promoters, annotate genomes, identify new RNAs and reconstruct models of transcriptional control. Although examples mainly concern mammalians, the discussion expands to other groups of eukaryotes, where these approaches are complementing genome sequencing.

Edited by: Piero Carninci
Imprint: Pan Stanford Publishing Pte Ltd
Country of Publication: Singapore
Dimensions: Height: 229mm, Width: 152mm, Spine: 15mm
Weight: 576g
ISBN: 9789814241342
ISBN 10: 9814241342
Pages: 266
Publication Date: 31 October 2009
Audience: College/higher education , General/trade , Primary , ELT Advanced
Format: Hardback
Publisher's Status: Active

Piero Carninci was born in Italy in 1965 and earned his doctorate in biological science at the University of Trieste in 1989. For six months from April 1989, he worked as a research associate at the International Center for Genetic Engineering and Biotechnology and then served as a health assistant in the Italian army. In 1990, he became a researcher at a biotech company called TALENT, after which he moved to RIKEN as a researcher in 1995. Since 2003, he has been working as a senior scientist at the Genome Science Laboratory at the RIKEN Frontier Research Institute and at the RIKEN Genomic Sciences Center.

Reviews for Cap-Analysis Gene Expression (CAGE): The Science of Decoding Genes Transcription

This is a comprehensive introduction to a powerful and important new technique that is transforming our understanding of gene regulation. This volume contains everything you need to know to become an expert in CAGE, from library construction to bioinformatic analysis of the voluminous data sets. -Gene E. Robinson, University of Illinois