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English
Oxford University Press
29 May 2017
For many people, taking some form of medication is part of everyday life, whether for mild or severe illness, acute or chronic disease, to target infection or to relieve pain. However for most it remains a mystery as to what happens once the drug has been taken into the body: how do the drugs actually work? Furthermore, by what processes are new drugs discovered and brought to market?

An Introduction to Medicinal Chemistry, sixth edition, provides an accessible and comprehensive account of this fascinating multidisciplinary field. Assuming little prior knowledge, the text is ideal for those studying the subject for the first time. Part one of the book introduces the principles of drug action via targets such as receptors and enzymes. The book goes on to explore how drugs work at the molecular level (pharmacodynamics), and the processes involved in ensuring a drug meets its target (pharmacokinetics). Further sections cover the processes by which drugs are discovered and designed, and what has to happen before a drug can be made available to the public.

The book concludes with a selection of current topics in medicinal chemistry, and a discussion of various key drug groups. The subject is brought to life throughout by engaging case studies highlighting particular drugs and the stories behind their discovery and development.

By:  
Imprint:   Oxford University Press
Country of Publication:   United Kingdom
Edition:   6th Revised edition
Dimensions:   Height: 265mm,  Width: 202mm,  Spine: 35mm
Weight:   1.604kg
ISBN:   9780198749691
ISBN 10:   0198749694
Pages:   912
Publication Date:  
Audience:   College/higher education ,  A / AS level
Format:   Paperback
Publisher's Status:   Active
PART A DRUG TARGETS - STRUCTURE AND FUNCTION; PART B PHARMACODYNAMICS AND PHARMACOKINETICS; PART C DRUG DISCOVERY, DESIGN, AND DEVELOPMENT; PART D TOOLS OF THE TRADE; PART E SELECTED TOPICS IN MEDICINAL CHEMISTRY; APPENDICES

Dr Graham Patrick gained his BSc Honours at Glasgow University, winning the McKay-Smith Prize for Chemistry. He completed his PhD with Professor Kirby and Professor Robins studying the biosynthesis of gliotoxin and related fungal metabolites. Following this, he worked in the pharmaceutical industry as a research chemist and radiochemist on a variety of projects that included topic areas such as opioids, antibacterial agents and antidepressants. His academic career has included positions at Leeds and Strathclyde Universities as well as the Australian National University. He joined the University of Paisley (now the University of the West of Scotland) in 1990, teaching medicinal chemistry and drug design.

Reviews for An Introduction to Medicinal Chemistry

`It is by far the best book on the market for medicinal chemistry and drug discovery.' Professor Steven Bull, University of Bath`Summarizes the chemistry of medicinal agents in a manner that easily facilitates understanding of the core principles in the context of pharmacological drug action and clinical therapeutics.' Professor John Marriott, University of Birmingham


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