Advances in Nutraceutical Applications in Cancer: Recent Research Trends and Clinical Applications

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Sheeba Varghese Gupta (University of South Florida, Tampa, FL, USA) Yashwant V Pathak

Advances in Nutraceutical Applications in Cancer

Recent Research Trends and Clinical Applications

Sheeba Varghese Gupta (University of South Florida, Tampa, FL, USA), Yashwant V Pathak

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English

CRC Press
11 November 2019

Food & beverage technology

Series: Nutraceuticals

Dietary supplements and nutraceuticals such as Vitamin A and D, Omega-3 and probiotics are used as part of the cancer treatment as complimenting the main therapy. Several Nutraceuticals have shown to boost the immune responses, while emerging clinical studies and other research suggests that some plant-based agents may, indeed, impact late-stage cancer, influencing molecular processes corrupted by tumor cells to evade detection, expand clonally, and invade surrounding tissues.

Advances in Nutraceutical Applications in Cancer: Recent Research Trends and Clinical Applications

is an attempt to collect evidence and related clinical information of application of Nutraceuticals to be used in cancer treatment or compliment the cancer treatment. It contains 16 chapters written by experts in related field’s and covers many different aspects of the formulation and development of Nutraceuticals for cancer applications. This book covers efficacy, safety and toxicological aspects of nutraceuticals. It also addresses various novel drug delivery systems of nutraceuticals with anticancer properties, as well as nutraceuticals as supplements for cancer prevention.

Features:

Offers a comprehensive view of neutraceuticals’ role in cancer prevention and treatment

Covers the applications and implications of neutraceuticals in prostate, colorectal, breast and gynecological cancers

Discusses the principles of neutrigenomics and neutrigenetics in cancer prevention

Explors the role of probiotics and micronutrients in cancer treatment and prevention

Nutraceuticals can alter the gut microbiota. Gut microbiome undergoes changes during the disease status and followed by the cancer treatment. Nutraceutical’s role in proliferation and prevention of gynecological cancers, nutraceutical’s role in proliferation and prevention of prostate cancer and role of micronutrients in cancer prevention, both pros and cons, are some of the topics discussed in various chapters in this book. This book is addressed to scientists, clinicians, and students who are working in the area of Nutraceutical applications in cancer treatment.

Edited by: Sheeba Varghese Gupta (University of South Florida Tampa FL USA), Yashwant V Pathak
Imprint: CRC Press
Country of Publication: United Kingdom
Dimensions: Height: 234mm, Width: 156mm,
Weight: 653g
ISBN: 9781138593916
ISBN 10: 1138593915
Series: Nutraceuticals
Pages: 348
Publication Date: 11 November 2019
Audience: Professional and scholarly , Undergraduate
Format: Hardback
Publisher's Status: Active

Contents Preface......................................................................................................................vii Editors .......................................................................................................................ix Contributors ..............................................................................................................xi Chapter 1 Role of Micronutrients in Cancer Prevention and Intervention—Pros and Cons ...............................................................1 Anjelika Chatwal and Yashwant V. Pathak Chapter 2 Nutraceuticals as Supplements for Cancer Prevention ....................... 19 Nicholas Micciche, Brianna Choyce, and Yashwant V. Pathak Chapter 3 Nutraceutical’s Role in Proliferation and Prevention of Prostate Cancer .............................................................................. 39 Raghunandan Yendapally and Donald Sikazwe Chapter 4 Nutraceutical’s Role in Proliferation and Prevention of Colorectal Cancer .......................................................................... 61 Mayur M. Patel, Shruti U. Rawal, and Jayvadan K. Patel Chapter 5 Nutraceuticals’ Role in Proliferation and Prevention of Breast Cancer ............................................................................... 115 Sadaf Aslam and Beata Casanas Chapter 6 Nutraceutical’s Role in Proliferation and Prevention of Gynecological Cancers ................................................................ 133 Aaishwarya B. Deshmukh, Jayvadan K. Patel, and Bharat Mishra Chapter 7 Mechanism and Role of Probiotics in Suppressing Bowel Cancer ..............................................................................153 Aaishwarya B. Deshmukh, Jayvadan K. Patel, and Bharat Mishra Chapter 8 Effect of Nutraceuticals on Gut Microbiota—What Is the Deal in Cancer? ................................................................................ 171 Andréa Burgess, Asra Sami, and Sheeba Varghese Gupta Chapter 9 Nutrigenomics and Nutrigenetics in Cancer Prevention .................. 191 Komal Parmar and Jayvadan K. Patel Chapter 10 Novel Drug Delivery Systems for Nutraceuticals with Anticancer Properties .......................................................................207 Priyanka Bhatt, Imran Vhora, and Rohan Lalani Chapter 11 Delivery Strategies and Formulation Approaches of Anticancer Nutraceuticals ................................................................ 239 Sunita Dahiya and Rajiv Dahiya Chapter 12 Efficacy, Safety, and Toxicological Aspects of Nutraceuticals ........269 Jayvadan K. Patel and Anita Patel Chapter 13 Dietary Habits and Susceptibility to Various Cancers ..................... 291 Kimberly Padawer and Yashwant V. Pathak Chapter 14 Indian Diet and Cancer Prevention ..................................................307 Vasudha Pritipaul, Asra Sami, and Sheeba Varghese Gupta Chapter 15 Dietary Isoflavones-Mechanism and Efficacy in Cancer Prevention and Treatment ................................................................. 325 Richa Dayaramani and Jayvadan K. Patel Index ...................................................................................................................... 341

Sheeba Varghese Gupta, MPharm, PhD, is an associate professor, Department of Pharmaceutical Sciences, College of Pharmacy, University of South Florida, Tampa, Florida. She received her PhD at Wayne State University, Michigan, and earned her MS in Pharmaceutical Chemistry from Bharati Vidhya Peeth Poona College of Pharmacy, University of Pune, Maharashtra, India. Her research interests are novel drug delivery systems, improving oral absorption of poorly absorbed drugs, and patient outcomes. She has authored many peer-reviewed publications, book chapters and abstracts. Dr. Yashwant V. Pathak completed his PhD in Pharmaceutical Technology at Nagpur University, India, and EMBA and MS in Conflict Management at Sullivan University. He is professor and associate dean for Faculty Affairs at Taneja College of Pharmacy, University of South Florida. Tampa, Florida. With extensive experience in academia as well as industry, he has more than 200 research publications, including research papers; chapters and reviews; 2 patent and 2 patent application; and 28 edited books published, including 12 books in nanotechnology and 10 in nutraceuticals and drug delivery systems. He has several books in cultural studies and conflict management. He has received several national and international awards. Dr. Pathak was a recipient of Fulbright Senior Scholar award for Indonesia in the year 2016–2017. Dr. Yashwant V. Pathak is also an adjunct professor at Faculty of Pharmacy, Airlangga University, Surabaya, Indonesia.

Reviews for Advances in Nutraceutical Applications in Cancer: Recent Research Trends and Clinical Applications

'This book attempts to summarize the existing evidence regarding mechanisms of action and applications of a broad range of nutraceuticals either for chemoprophylaxis of solid tumors or as supplements to alleviate chemotherapy-induced toxicities. In addition, two chapters discuss delivery systems utilized for administration of nutraceuticals. One chapter is dedicated to discussion, although rather limited, of the Indian diet and its role in cancer prevention; this is a valuable and unique feature since India has the lowest incidence of cancers in comparison to the Americas, Africa, and China. 'The purpose [of this book] is to summarize the data on the role of nutraceuticals in cancer management. This is a highly noteworthy and ambitious goal. The results of multiple surveys, personal encounters, and experiences shared by healthcare practitioners reflect a tremendous public interest on the subject as well as consumption of the supplements in discussion. It is difficult to underestimate the usefulness of such a book for medical and allied health educational purposes.' -- Anna Dushenkov, Fairleigh Dickinson University